Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis. (Q42519967)

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9 December 2019

title

Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis (English)

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13

Mathias Jucker

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9 December 2019

12

Matthias Staufenbiel

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9 December 2019

author name string

Sonia Boncristiano

1

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9 December 2019

Michael E Calhoun

2

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9 December 2019

Peter H Kelly

3

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9 December 2019

Michelle Pfeifer

4

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9 December 2019

Luca Bondolfi

5

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9 December 2019

Martina Stalder

6

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9 December 2019

Amie L Phinney

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9 December 2019

Dorothee Abramowski

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9 December 2019

Christine Sturchler-Pierrat

9

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9 December 2019

Albert Enz

10

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9 December 2019

Bernd Sommer

11

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9 December 2019

language of work or name

English

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publication date

1 April 2002

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9 December 2019

published in

Journal of Neuroscience

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volume

22

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9 December 2019

issue

8

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9 December 2019

page(s)

3234-3243

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A rapid radiochemical method for the determination of choline acetyltransferase

9 December 2019

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Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice

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β-Amyloid peptides as direct cholinergic neuromodulators: a missing link?

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beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice.

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Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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Progressive age-related impairment of cognitive behavior in APP23 transgenic mice

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Neocortical infarction in subhuman primates leads to restricted morphological damage of the cholinergic neurons in the nucleus basalis of Meynert

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Animal models of Alzheimer's disease: experimental cholinergic denervation

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New stereological methods for counting neurons

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Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain

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Cholinergic function and intellectual decline in Alzheimer's disease

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Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

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Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains

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Some new, simple and efficient stereological methods and their use in pathological research and diagnosis.

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Estimating neuron dendritic length in 3D from total vertical projections and from vertical slices.

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Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

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Convergent cholinergic activities in aging and Alzheimer's disease

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Decrease of neocortical choline acetyltransferase after lesion of the globus pallidus in the rat

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A brain regional analysis of morphologic and cholinergic abnormalities in Alzheimer's disease.

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Effect of alkalizing agents on the processing of the beta-amyloid precursor protein.

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An Immunological Study of Rat Acetylcholinesterase: Comparison with Acetylcholinesterases from Other Vertebrates

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12 December 2020

Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes

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12 December 2020

Immunocytochemical distribution of peptidergic and cholinergic fibers in the human amygdala: their depletion in Alzheimer's disease and morphologic alteration in non-demented elderly with numerous senile plaques.

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Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.

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The cholinergic hypothesis of geriatric memory dysfunction

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Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

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A modified histochemical technique to visualize acetylcholinesterase-containing axons

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Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease.

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The cholinergic deficit coincides with Abeta deposition at the earliest histopathologic stages of Alzheimer disease.

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A new and rapid colorimetric determination of acetylcholinesterase activity

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Pharmacological drug treatment of Alzheimer disease: the cholinergic hypothesis revisited.

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Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains

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Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

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Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43.

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Tau protein and the neurofibrillary pathology of Alzheimer's disease

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12 December 2020

Retrograde changes in cholinergic neurons in the basal forebrain of the rat following cortical damage

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12 December 2020

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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12 December 2020

Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain.

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12 December 2020

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

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Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.

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An unbiased method for estimation of total epidermal nerve fibre length

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

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Cell loss and shrinkage in the nucleus basalis Meynert complex in Alzheimer's disease

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12 December 2020

Relationship between plaques, tangles, and loss of cortical cholinergic fibers in Alzheimer disease

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Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

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Cholinesterases in the amyloid angiopathy of Alzheimer's disease

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Neurofibrillary degeneration and cell loss in the nucleus basalis in comparison to cortical Alzheimer pathology.

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12 December 2020

Association of microglia with amyloid plaques in brains of APP23 transgenic mice

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12 December 2020

Brain trauma in aged transgenic mice induces regression of established abeta deposits

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12 December 2020

Neuron loss in APP transgenic mice

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12 December 2020

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

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12 December 2020

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12 December 2020

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

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12 December 2020

10.1523/JNEUROSCI.22-08-03234.2002

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11943824 AND SRC:MED&resulttype=core&format=json

9 December 2019

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9 December 2019

PubMed publication ID

11943824

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