DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts (Q42491492)

1 November 2017

title

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts (English)

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regulation of gene expression

1 November 2017

0 references

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21753787

7 December 2024

1

E. Karouzakis

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C. Kolling

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M. Neidhart

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C. Ospelt

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author name string

Y. Rengel

2

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A. Jüngel

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R. E. Gay

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B. A. Michel

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P. P. Tak

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S. Gay

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7 December 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21753787

7 December 2024

publication date

14 July 2011

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full work available at URL

1 November 2017

https://www.zora.uzh.ch/id/eprint/52986/1/Karouzakis_et_al_DNA_methylation.pdf

file format

Portable Document Format

online access status

open access

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https://www.nature.com/articles/gene201145.pdf

7 December 2024

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/GENE.2011.45

https://www.nature.com/articles/gene201145

7 December 2024

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 December 2024

1 reference

1 November 2017

volume

12

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1 November 2017

issue

8

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1 November 2017

page(s)

643-652

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The role of resident synovial cells in destructive arthritis

1 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Methyl CpG-binding proteins and transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Epigenetic reprogramming in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The genetics and epigenetics of autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

21 January 2018

Epigenetics in cancer

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Novel cellular genes essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Localization of the alpha-chemokine SDF-1 and its receptor CXCR4 in idiopathic inflammatory myopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4 T cell accumulation in rheumatoid arthritis synovium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Fibroblast-like synoviocytes support B-cell pseudoemperipolesis via a stromal cell-derived factor-1- and CD106 (VCAM-1)-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

CXCL12 chemokine up-regulates bone resorption and MMP-9 release by human osteoclasts: CXCL12 levels are increased in synovial and bone tissue of rheumatoid arthritis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Synovectomy reduces stromal-cell-derived factor-1 (SDF-1) which is involved in the destruction of cartilage in osteoarthritis and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Epigenetic changes in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Gene silencing in cancer in association with promoter hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Analysis of repetitive element DNA methylation by MethyLight

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Primer: epigenetics of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4 lupus T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

c/EBPbeta is a major regulatory element driving transcriptional activation of the CXCL12 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Functional characterization of SDF-1 proximal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Synoviocyte-derived CXCL12 is displayed on endothelium and induces angiogenesis in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The chemokine receptor CXCR4 is regulated by DNA methylation in pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Characterization of the G-protein linked orphan receptor GPRN1/RDC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

AMD3100 is a CXCR7 ligand with allosteric agonist properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Arrestins: ubiquitous regulators of cellular signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The role of DNA hypomethylation in the control of stromelysin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The AP-1 site and MMP gene regulation: what is all the fuss about?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

MethPrimer: designing primers for methylation PCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 January 2021

Chemokines regulate IL-6 and IL-8 production by fibroblast-like synoviocytes from patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 January 2021

Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 January 2021

Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4 and CD8 T cell migration within synovial tissue

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 January 2021

Human inflammatory synovial fibroblasts induce enhanced myeloid cell recruitment and angiogenesis through a hypoxia-inducible transcription factor 1alpha/vascular endothelial growth factor-mediated pathway in immunodeficient mice

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 January 2021

The dual inhibitor of lipoxygenase and cyclooxygenase ML3000 decreases the expression of CXCR3 ligands

1 reference

https://api.crossref.org/works/10.1038/GENE.2011.45

7 January 2021

Identifiers

DOI

10.1038/GENE.2011.45

1 reference

1 November 2017

1 reference