Oscillatory mTOR inhibition and Treg increase in kidney transplantation. (Q42478371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26077103 AND SRC:MED&resulttype=core&format=json

17 February 2020

title

Oscillatory mTOR inhibition and Treg increase in kidney transplantation (English)

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17 February 2020

2

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17 February 2020

Mario Galgani

10

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17 February 2020

Giuseppe Terrazzano

11

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17 February 2020

author name string

M Sabbatini

1

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17 February 2020

A T Palatucci

3

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17 February 2020

V Rubino

4

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17 February 2020

S Federico

5

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17 February 2020

A Giovazzino

6

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17 February 2020

L Apicella

7

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17 February 2020

M Santopaolo

8

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17 February 2020

G Matarese

9

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17 February 2020

publication date

28 August 2015

1 reference

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Clinical and Experimental Immunology

17 February 2020

published in

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17 February 2020

volume

182

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17 February 2020

issue

2

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17 February 2020

page(s)

230-240

1 reference

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17 February 2020

1 reference

Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era.

21 January 2018

1 reference

Meta-analysis of calcineurin-inhibitor-sparing regimens in kidney transplantation

21 January 2018

1 reference

Reduced exposure to calcineurin inhibitors in renal transplantation

21 January 2018

1 reference

Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients

21 January 2018

1 reference

Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study

21 January 2018

1 reference

TOR signaling in growth and metabolism

21 January 2018

1 reference

Actively acquired tolerance of foreign cells

21 January 2018

1 reference

Control of autoimmunity by naturally arising regulatory CD4 T cells

21 January 2018

1 reference

Foxp3 CD25 CD4 natural regulatory T cells in dominant self-tolerance and autoimmune disease

21 January 2018

1 reference

The lifestyle of naturally occurring CD4 CD25 Foxp3 regulatory T cells

21 January 2018

1 reference

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

21 January 2018

1 reference

Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways

21 January 2018

1 reference

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

21 January 2018

1 reference

Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4 effector T cell responses

21 January 2018

1 reference

An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.

21 January 2018

1 reference

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8 T Cell Differentiation

21 January 2018

1 reference

Biomarker Development for the Clinical Activity of the mTOR Inhibitor Everolimus (RAD001): Processes, Limitations, and Further Proposals

21 January 2018

1 reference

SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo

21 January 2018

1 reference

Targeting mTOR Pathways in Human Malignancies

21 January 2018

1 reference

Time now to TORC the TORC? New developments in mTOR pathway inhibition in lymphoid malignancies.

21 January 2018

1 reference

Development of everolimus, a novel oral mTOR inhibitor, across a spectrum of diseases

21 January 2018

1 reference

Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial

21 January 2018

1 reference

Eculizumab treatment modifies the immune profile of PNH patients.

21 January 2018

1 reference

21 January 2018

The biology of NKT cells

1 reference

PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

21 January 2018

1 reference

mTOR signaling: PLD takes center stage

21 January 2018

1 reference

Role of the p70(S6K) pathway in regulating the actin cytoskeleton and cell migration

21 January 2018

1 reference

Effect of everolimus on the immunomodulation of the human neutrophil inflammatory response and activation

21 January 2018

1 reference

Neutrophils in the activation and regulation of innate and adaptive immunity

21 January 2018

1 reference

Chemokines: directing leukocyte infiltration into allografts

21 January 2018

1 reference

Elevated serum levels of the CXCR3 chemokine ITAC are associated with the development of transplant coronary artery disease

21 January 2018

1 reference

A Central Role for mTOR Kinase in Homeostatic Proliferation Induced CD8 T Cell Memory and Tumor Immunity

21 January 2018

1 reference

Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells

21 January 2018

1 reference

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

21 January 2018

1 reference

Low-affinity ligands for the TCR drive proliferation of mature CD8 T cells in lymphopenic hosts

21 January 2018

1 reference

mTOR and lymphocyte metabolism

21 January 2018

1 reference

Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

21 January 2018

1 reference

Impact of immunosuppressants on the therapeutic efficacy of in vitro-expanded CD4 CD25 Foxp3 regulatory T cells in allotransplantation

21 January 2018

1 reference

Conversion from calcineurin inhibitor to mycophenolate mofetil-based immunosuppression changes the frequency and phenotype of CD4 FOXP3 regulatory T cells

21 January 2018

1 reference

The effect of mammalian target of rapamycin inhibition on T helper type 17 and regulatory T cell differentiation in vitro and in vivo in kidney transplant recipients

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608513

Clinical evidence on the use of anti-mTOR drugs in renal transplantation

3 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608513

Molecular characterization of the gene locus of the human cell proliferation-associated nuclear protein defined by monoclonal antibody Ki-67.

3 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608513

Immunosuppressive drugs on inducing Ag-specific CD4( )CD25( )Foxp3( ) Treg cells during immune response in vivo

3 November 2018

1 reference

12 December 2020

Cyclosporine nephrotoxicity

1 reference

12 December 2020

Immune dysregulation and dyserythropoiesis in the myelodysplastic syndromes

1 reference

12 December 2020

Early chemokine cascades in murine cardiac grafts regulate T cell recruitment and progression of acute allograft rejection

1 reference

12 December 2020

Conversion to proliferation signal inhibitors-based immunosuppressive regimen in kidney transplantation: to whom and when?

1 reference

12 December 2020

Identifiers

DOI

10.1111/CEI.12669

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26077103 AND SRC:MED&resulttype=core&format=json

17 February 2020

PMC publication ID

4608513

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26077103 AND SRC:MED&resulttype=core&format=json