K-252b Is a Selective and Nontoxic Inhibitor of Nerve Growth Factor Action on Cultured Brain Neurons (Q42471483)

1 November 2017

title

K-252b Is a Selective and Nontoxic Inhibitor of Nerve Growth Factor Action on Cultured Brain Neurons (English)

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.1991.TB08243.X

12 December 2022

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.1991.TB08243.X

12 December 2022

author name string

B. Knüsel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1861160

12 December 2022

F. Hefti

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1861160

12 December 2022

language of work or name

English

0 references

publication date

1 September 1991

1 reference

full work available at URL

1 November 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111/j.1471-4159.1991.tb08243.x

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.1991.TB08243.X

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.1991.tb08243.x/fullpdf

12 December 2022

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.1991.TB08243.X

Journal of Neurochemistry

12 December 2022

published in

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1 November 2017

volume

57

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1 November 2017

issue

3

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1 November 2017

page(s)

955-962

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Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture

1 November 2017

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Trophic factors and neuronal survival

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Differential effects of the protein kinase inhibitor K-252a on the in vitro survival of chick embryonic neurons

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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NICER elements: a family of nerve growth factor-inducible cAMP-extinguishable retrovirus-like elements.

21 January 2018

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K-252a specifically inhibits the survival and morphological differentiation of NGF-dependent neurons in primary cultures of human dorsal root ganglia.

21 January 2018

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Characterization of receptor tyrosine-specific protein kinases by the use of inhibitors. Staurosporine is a 100-times more potent inhibitor of insulin receptor than IGF-I receptor.

21 January 2018

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Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription

21 January 2018

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K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells

21 January 2018

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Expression and structure of the human NGF receptor

21 January 2018

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K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

21 January 2018

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Development of cholinergic pedunculopontine neurons in vitro: comparison with cholinergic septal cells and response to nerve growth factor, ciliary neuronotrophic factor, and retinoic acid

21 January 2018

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Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3.

21 January 2018

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Induction of the proto-oncogene fos by nerve growth factor

21 January 2018

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Nerve growth factor selectively increases cholinergic markers but not neuropeptides in rat basal forebrain in culture

21 January 2018

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Gene transfer and molecular cloning of the rat nerve growth factor receptor

21 January 2018

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Two forms of the basic fibroblast growth factor receptor-like mRNA are expressed in the developing mouse brain

21 January 2018

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Binding of brain-derived neurotrophic factor to the nerve growth factor receptor

21 January 2018

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21 January 2018

Neurotrophic molecules

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Staurosporine, a potent inhibitor of phospholipid/Ca dependent protein kinase

21 January 2018

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Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene

21 January 2018

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A second messenger required for nerve growth factor biological activity?

21 January 2018

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Specific stimulation of in vitro maturation of mesencephalic dopaminergic neurones by striatal membranes

21 January 2018

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Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture

21 January 2018

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A rapid radiochemical method for the determination of choline acetyltransferase

12 December 2022

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NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?

12 December 2022

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Basic fibroblast growth factor promotes in vitro survival and cholinergic development of rat septal neurons: comparison with the effects of nerve growth factor

12 December 2022

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Nerve growth factor mediates phosphorylation of specific proteins

12 December 2022

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Development of septal cholinergic neurons in culture: plating density and glial cells modulate effects of NGF on survival, fiber growth, and expression of transmitter-specific enzymes

12 December 2022

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Blockage of nerve growth factor action in PC12h cells by staurosporine, a potent protein kinase inhibitor

12 December 2022

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Nerve growth factor (NGF) stimulation of cholinergic telencephalic neurons in aggregating cell cultures.

12 December 2022

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K-252a, a potent inhibitor of protein kinase C from microbial origin

12 December 2022

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Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II.

12 December 2022

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K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

12 December 2022

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https://api.crossref.org/works/10.1111/J.1471-4159.1991.TB08243.X

Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells

12 December 2022

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Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility

12 December 2022

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Choline acetyltransferase activity in striatum of neonatal rats increased by nerve growth factor

12 December 2022

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Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons

12 December 2022

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A nerve growth factor-dependent protein kinase that phosphorylates microtubule-associated proteins in vitro: possible involvement of its activity in the outgrowth of neurites from PC12 cells.

12 December 2022

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Pressure microinjection of nerve growth factor and anti-nerve growth factor into the nucleus and cytoplasm: lack of effects on neurite outgrowth from pheochromocytoma cells

12 December 2022

46

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Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5'-S-methyladenosine in PC12 cells

12 December 2022

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1 reference

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The physiological function of nerve growth factor in the central nervous system: comparison with the periphery

12 December 2022

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Mimicry and inhibition of nerve growth factor effects: interactions of staurosporine, forskolin, and K252a in PC12 cells and normal rat chromaffin cells in vitro

12 December 2022

52

1 reference

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12 December 2022

Identifiers

1 reference

1 November 2017

1 reference