Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1. (Q42468291)

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English	Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.	scientific article

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22 February 2020

Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1 (English)

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22 February 2020

Uri Kahanovitch

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22 February 2020

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Vladimir Tsemakhovich

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22 February 2020

Moran Rubinstein

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Boaz Styr

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Ruth Castel

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Sagit Peleg

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Galit Tabak

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Carmen W Dessauer

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Tatiana Ivanina

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10 November 2014

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22 February 2020

Journal of Physiology

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22 February 2020

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22 February 2020

G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K channel (GIRK)

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Two distinct aspects of coupling between Gα(i) protein and G protein-activated K channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K channel subunit

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Specific regions of heteromeric subunits involved in enhancement of G protein-gated K channel activity

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Constitutively active G-protein-gated inwardly rectifying K channels in dendrites of hippocampal CA1 pyramidal neurons.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Signalling Via the G Protein-Activated K Channels

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Inhibition of function in Xenopus oocytes of the inwardly rectifying G-protein-activated atrial K channel (GIRK1) by overexpression of a membrane-attached form of the C-terminal tail

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Identification of a Gialpha binding site on type V adenylyl cyclase

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Dual regulation of G proteins and the G-protein-activated K channels by lithium

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Molecular basis for interactions of G protein betagamma subunits with effectors

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Identification of a potassium channel site that interacts with G protein betagamma subunits to mediate agonist-induced signaling

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Cloning of a Xenopus laevis inwardly rectifying K channel subunit that permits GIRK1 expression of IKACh currents in oocytes

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Non-canonical signaling and localizations of heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Inwardly rectifying potassium channels: their structure, function, and physiological roles

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

G protein-coupled mechanisms and nervous signaling

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K channels

2 references

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270501

30 September 2018

Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K channel is important for channel activation

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K channel

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K channel.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2 channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Differential effects of genetically-encoded Gβγ scavengers on receptor-activated and basal Kir3.1/Kir3.4 channel current in rat atrial myocytes

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

The G protein alpha subunit has a key role in determining the specificity of coupling to, but not the activation of, G protein-gated inwardly rectifying K( ) channels

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K channel (GIRK) expressed in Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

G protein-coupled inwardly rectifying K channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Structural basis for modulation of gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by i/o-family G protein α subunit (Gαi/o).

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Functional stoichiometry and local enrichment of calmodulin interacting with Ca2 channels

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Kir3 channel signaling complexes: focus on opioid receptor signaling

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Crystal structure of a Kir3.1-prokaryotic Kir channel chimera

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

G(alpha)(i) controls the gating of the G protein-activated K( ) channel, GIRK.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Elucidation of the gating of the GIRK channel using a spectroscopic approach

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K channels.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Galphai3 primes the G protein-activated K channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K channel by GalphaiGDP and Gbetagamma.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

NMDA and GABAB (KIR) conductances: the "perfect couple" for bistability.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na in a reconstituted system

1 reference

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21 January 2018

X-ray structure of the mammalian GIRK2–βγ G-protein complex

1 reference

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21 January 2018

Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN.

1 reference

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21 January 2018

Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity

1 reference

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21 January 2018

Slow modal gating of single G protein-activated K channels expressed in Xenopus oocytes

1 reference

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21 January 2018

NMR Analyses of the Gβγ Binding and Conformational Rearrangements of the Cytoplasmic Pore of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1)

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

The role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels

1 reference

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21 January 2018

G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons.

1 reference

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30 September 2018

Imaging plasma membrane proteins in large membrane patches of Xenopus oocytes

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30 September 2018

Na Promotes the Dissociation between GαGDPand Gβγ, Activating G Protein-gated K Channels

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2014.283218

21 January 2018

Distinct specificities of inwardly rectifying K( ) channels for phosphoinositides

1 reference

https://pubmed.ncbi.nlm.nih.gov/25384780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPCR-Kir channel signaling complexes: defining rules of engagement

1 reference

https://pubmed.ncbi.nlm.nih.gov/25384780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G beta gamma binds directly to the G protein-gated K channel, IKACh

1 reference

https://pubmed.ncbi.nlm.nih.gov/25384780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1113/JPHYSIOL.2014.283218

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25384780 AND SRC:MED&resulttype=core&format=json

22 February 2020

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22 February 2020

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