Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system (Q42434849)

31 October 2017

title

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system (English)

1 reference

31 October 2017

1 reference

Richard Killick

8

0 references

Christopher Thrasivoulou

object named as

Christopher Thrasivoulou

6

0 references

Simon Lovestone

object named as

Simon Lovestone

7

0 references

author name string

Raya Al-Shawi

1

1 reference

31 October 2017

Angela Hafner

2

1 reference

31 October 2017

Jessica Olsen

3

1 reference

31 October 2017

Soyon Chun

4

1 reference

31 October 2017

Saba Raza

5

1 reference

31 October 2017

Paul Simons

9

1 reference

31 October 2017

Timothy Cowen

10

1 reference

31 October 2017

language of work or name

English

0 references

publication date

1 April 2008

1 reference

European Journal of Neuroscience

31 October 2017

published in

1 reference

31 October 2017

volume

27

1 reference

31 October 2017

issue

8

1 reference

31 October 2017

page(s)

2103-2114

1 reference

Mature pig oligodendrocytes rapidly process human recombinant pro-nerve growth factor and do not undergo cell death

31 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Grasping objects: the cortical mechanisms of visuomotor transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Selective vulnerability in adult and ageing mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Plasticity in adult and ageing sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Restricted diet rescues rat enteric motor neurones from age related cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Hippocampal NGF levels are not reduced in the aged Fischer 344 rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Monoclonal antibody rat 401 recognizes Schwann cells in mature and developing peripheral nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Responsiveness of sympathetic and sensory iridial nerves to NGF treatment in young and aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Loss of calbindin-D28k from aging human cholinergic basal forebrain: relation to neuronal loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Impaired spatial learning in aged rats is associated with loss of p75-positive neurons in the basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Regulation of cell survival by secreted proneurotrophins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Sortilin is essential for proNGF-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Serum-free culture of dissociated, purified adult and aged sympathetic neurons and quantitative assays of growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Differential regulation of survival and growth in adult sympathetic neurons: an in vitro study of neurotrophin responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Induction of apoptosis by the low-affinity NGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1460-9568.2008.06152.X

10.1111/J.1460-9568.2008.06152.X

21 January 2018

Identifiers

DOI

1 reference

31 October 2017

1 reference