mTOR Inhibition: Reduced Insulin Secretion and Sensitivity in a Rat Model of Metabolic Syndrome (Q42418240)

30 October 2017

mTOR Inhibition: Reduced Insulin Secretion and Sensitivity in a Rat Model of Metabolic Syndrome (English)

1 reference

30 October 2017

1 reference

1

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12 June 2020

María José Ramírez-Bajo

2

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12 June 2020

Elisenda Banon-Maneus

3

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12 June 2020

Fritz Diekmann

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12 June 2020

author name string

Daniel Moya-Rull

4

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12 June 2020

Pedro Ventura-Aguiar

5

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12 June 2020

Natalia Hierro-Garcia

6

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12 June 2020

Marta Lazo-Rodriguez

7

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12 June 2020

Ignacio Revuelta

8

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12 June 2020

Armando Torres

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12 June 2020

Federico Oppenheimer

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12 June 2020

Josep M Campistol

11

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12 June 2020

publication date

22 January 2016

1 reference

30 October 2017

Transplantation direct

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12 June 2020

volume

2

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12 June 2020

issue

2

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12 June 2020

page(s)

e65

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Risk of metabolic complications in kidney transplantation after conversion to mTOR inhibitor: a systematic review and meta-analysis

12 June 2020

cites work

1 reference

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Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms.

28 May 2018

1 reference

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Insulin resistance in patients with chronic kidney disease

28 May 2018

1 reference

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Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats

28 May 2018

1 reference

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The association of early post-transplant glucose levels with long-term mortality.

28 May 2018

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Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus

28 May 2018

1 reference

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Sirolimus is associated with new-onset diabetes in kidney transplant recipients.

28 May 2018

1 reference

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Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome

28 May 2018

1 reference

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Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

28 May 2018

1 reference

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Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells

28 May 2018

1 reference

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Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

28 May 2018

1 reference

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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation

28 May 2018

1 reference

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Diabetes mellitus and genetically programmed defects in beta-cell function

28 May 2018

1 reference

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Banting lecture 1988. Role of insulin resistance in human disease

28 May 2018

1 reference

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Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents

28 May 2018

1 reference

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The higher diabetogenic risk of tacrolimus depends on pre-existing insulin resistance. A study in obese and lean Zucker rats.

28 May 2018

1 reference

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Role of insulin resistance indices in predicting new-onset diabetes after kidney transplantation.

16 August 2018

1 reference

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Effect of different immunosuppressive regimens on the evolution of distinct metabolic parameters: evidence from the Symphony study

16 August 2018

1 reference

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Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study

16 August 2018

1 reference

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Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients

16 August 2018

1 reference

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mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946492

Rapamycin impairs in vivo proliferation of islet beta-cells.

16 August 2018

1 reference

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Reduced exposure to calcineurin inhibitors in renal transplantation

16 August 2018

1 reference

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Reduced incidence of new-onset posttransplantation diabetes mellitus during the last decade

16 August 2018

1 reference

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Tacrolimus and sirolimus cause insulin resistance in normal sprague dawley rats

16 August 2018

1 reference

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Mechanisms of compensatory beta-cell growth in insulin-resistant rats: roles of Akt kinase.

16 August 2018

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beta-Cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis

16 August 2018

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Stable and functional regeneration of pancreatic beta-cell population in nSTZ-rats treated with tungstate

16 August 2018

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Diabetes mellitus after kidney transplantation in the United States

16 August 2018

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beta-Cell dysfunction rather than insulin resistance is the main contributing factor for the development of postrenal transplantation diabetes mellitus

16 August 2018

1 reference

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Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: problems and prospects.

16 August 2018

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Factor analysis of the metabolic syndrome: obesity vs insulin resistance as the central abnormality

16 August 2018

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Influence of diabetes mellitus on patient and graft survival in recipients of kidney transplantation

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27500257

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/TXD.0000000000000576

1 reference

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12 June 2020

1 reference

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12 June 2020

PubMed publication ID

27500257

1 reference