Deamidation destabilizes and triggers aggregation of a lens protein, betaA3-crystallin. (Q42417058)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18567786 AND SRC:MED&resulttype=core&format=json

9 January 2020

title

Deamidation destabilizes and triggers aggregation of a lens protein, betaA3-crystallin (English)

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9 January 2020

1

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9 January 2020

Julie T. Oxford

series ordinal

2

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9 January 2020

3

Borries Demeler

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9 January 2020

author name string

Kirsten J Lampi

series ordinal

4

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9 January 2020

language of work or name

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20 June 2008

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9 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18567786 AND SRC:MED&resulttype=core&format=json

9 January 2020

volume

17

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9 January 2020

issue

9

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9 January 2020

page(s)

1565-1575

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Association properties of betaB1- and betaA3-crystallins: ability to form heterotetramers

9 January 2020

cites work

1 reference

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Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions

28 May 2018

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Proteomic analysis of water insoluble proteins from normal and cataractous human lenses.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Protein-protein interactions among human lens acidic and basic beta-crystallins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Deamidation alters the structure and decreases the stability of human lens betaA3-crystallin

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Analysis of betaB1-crystallin unfolding equilibrium by spin and fluorescence labeling: evidence of a dimeric intermediate

28 May 2018

1 reference

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28 May 2018

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Truncation of motifs III and IV in human lens betaA3-crystallin destabilizes the structure

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Deamidation in human lens betaB2-crystallin destabilizes the dimer

28 May 2018

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Stepwise deamidation of ribonuclease A at five sites determined by top down mass spectrometry

28 May 2018

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Identification of post-translational modifications by blind search of mass spectra.

28 May 2018

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Global data on visual impairment in the year 2002

28 May 2018

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CDtool-an integrated software package for circular dichroism spectroscopic data processing, analysis, and archiving

28 May 2018

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Crystallins in water soluble-high molecular weight protein fractions and water insoluble protein fractions in aging and cataractous human lenses

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data

28 May 2018

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Characterization of the G91del CRYBA1/3-crystallin protein: a cause of human inherited cataract

28 May 2018

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Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide

28 May 2018

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Crystal structure of truncated human βB1‐crystallin

28 May 2018

1 reference

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Dimerization of human XPA and formation of XPA2-RPA protein complex

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Low levels of asparagine deamidation can have a dramatic effect on aggregation of amyloidogenic peptides: implications for the study of amyloid formation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Prediction of protein deamidation rates from primary and three-dimensional structure

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Analyzing protein circular dichroism spectra for accurate secondary structures

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Deamidation and isoaspartate formation in smeared tau in paired helical filaments. Unusual properties of the microtubule-binding domain of tau.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

28 May 2018

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N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Evolution and the Distribution of Glutaminyl and Asparaginyl Residues in Proteins

28 May 2018

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Determination and analysis of urea and guanidine hydrochloride denaturation curves

28 May 2018

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X-ray analysis of beta B2-crystallin and evolution of oligomeric lens proteins

28 May 2018

1 reference

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Tissue transglutaminase catalyzes the deamidation of glutamines in lens betaB(2)- and betaB(3)-crystallins

28 May 2018

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Reliable detection of deamidated peptides from lens crystallin proteins using changes in reversed-phase elution times and parent ion masses

16 August 2018

1 reference

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Quantitative measurement of young human eye lens crystallins by direct injection Fourier transform ion cyclotron resonance mass spectrometry

16 August 2018

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Sedimentation velocity analysis of highly heterogeneous systems

16 August 2018

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Prediction of primary structure deamidation rates of asparaginyl and glutaminyl peptides through steric and catalytic effects

16 August 2018

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The stability of human acidic beta-crystallin oligomers and hetero-oligomers

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Human beta-crystallins modified by backbone cleavage, deamidation and oxidation are prone to associate

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Novel method for evaluation of the oligomeric structure of membrane proteins

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2525517

Short-range order of crystallin proteins accounts for eye lens transparency

16 August 2018

1 reference

12 December 2020

Age-dependent deamidation of alpha B-crystallin

1 reference

12 December 2020

Simultaneous racemization and isomerization at specific aspartic acid residues in alpha B-crystallin from the aged human lens

1 reference

12 December 2020

Monomer-dimer equilibrium of normal and modified beta A3-crystallins: experimental determination and molecular modeling

1 reference

12 December 2020

Deamidation of Human βB1 Alters the Elongated Structure of the Dimer

1 reference

12 December 2020

Glutamine deamidation destabilizes human gammaD-crystallin and lowers the kinetic barrier to unfolding

1 reference

12 December 2020

Post-translational modifications in the nuclear region of young, aged, and cataract human lenses

1 reference

12 December 2020

Deamidation of specific glutamine residues from alpha-A crystallin during aging of the human lens

1 reference

12 December 2020

Identifiers

DOI

10.1110/PS.035410.108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18567786 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18567786 AND SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

18567786

1 reference