Progesterone and related compounds in hepatocellular carcinoma: basic and clinical aspects. (Q42182106)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

2 references

15 October 2020

25 October 2022

Progesterone and related compounds in hepatocellular carcinoma: basic and clinical aspects (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

medroxyprogesterone acetate

25 February 2020

main subject

hepatocellular carcinoma

1 reference

15 October 2020

1 reference

15 October 2020

1 reference

hormonal antineoplastic agent

13 November 2019

1 reference

15 October 2020

1 reference

PubMed publication ID

23484104

sexual characteristic

1 reference

PubMed publication ID

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

author name string

Chien-Wei Chang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

Ren-Jie Wei

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

Shen-Nien Wang

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

English

0 references

publication date

16 January 2013

6 references

3 April 2019

19 June 2019

13 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

15 October 2020

25 October 2022

BioMed Research International

6 references

3 April 2019

19 June 2019

13 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

15 October 2020

25 October 2022

2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

page(s)

290575

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

25 February 2020

copyright license

5 references

3 April 2019

19 June 2019

13 November 2019

15 October 2020

on focus list of Wikimedia project

25 October 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

26 October 2017

1 reference

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Steroid receptor phosphorylation: a key modulator of multiple receptor functions

26 October 2017

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Progestin effects on breast cancer cell proliferation, proteases activation, and in vivo development of metastatic phenotype all depend on progesterone receptor capacity to activate cytoplasmic signaling pathways.

26 October 2017

1 reference

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Src-dependent signalling pathway regulation by sex-steroid hormones: therapeutic implications

26 October 2017

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The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle

26 October 2017

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Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells

26 October 2017

1 reference

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Liver fibrosis in women with chronic hepatitis C: evidence for the negative role of the menopause and steatosis and the potential benefit of hormone replacement therapy

26 October 2017

1 reference

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26 October 2017

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Potential role of leptin expression in hepatocellular carcinoma

26 October 2017

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Opposing effects of oestradiol and progesterone on intracellular pathways and activation processes in the oxidative stress induced activation of cultured rat hepatic stellate cells

26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases

26 October 2017

1 reference

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The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo.

26 October 2017

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Medroxyprogesterone acetate antagonizes the effects of estrogen treatment on social and sexual behavior in female macaques

26 October 2017

1 reference

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Systematic review of megestrol acetate in the treatment of anorexia-cachexia syndrome.

26 October 2017

1 reference

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Classification and pharmacology of progestins

26 October 2017

1 reference

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Progesterone receptor interacting coregulatory proteins and cross talk with cell signaling pathways

26 October 2017

1 reference

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Impact of oestrogens on the progression of liver disease

26 October 2017

1 reference

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Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells

26 October 2017

1 reference

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Hepatocellular carcinoma: an epidemiologic view

26 October 2017

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Hepatoma associated with androgen therapy for aplastic anemia

26 October 2017

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26 October 2017

1 reference

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Mechanisms of tamoxifen-induced apoptosis

26 October 2017

1 reference

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Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases

26 October 2017

1 reference

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Hormonal therapy with megestrol in inoperable hepatocellular carcinoma characterized by variant oestrogen receptors

26 October 2017

1 reference

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Molecular chaperone interactions with steroid receptors: an update

26 October 2017

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Role of the androgen receptor in human breast cancer

26 October 2017

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Sigma-2 receptors as a biomarker of proliferation in solid tumours

26 October 2017

1 reference

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Megestrol acetate: promises and pitfalls

26 October 2017

1 reference

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Non-transcriptional action of oestradiol and progestin triggers DNA synthesis.

26 October 2017

1 reference

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Distinguishing androgen receptor agonists and antagonists: distinct mechanisms of activation by medroxyprogesterone acetate and dihydrotestosterone

26 October 2017

1 reference

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Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats

26 October 2017

1 reference

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Physiological Action of Progesterone in Target Tissues*

26 October 2017

1 reference

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Tamoxifen for the treatment of malignancies other than breast and endometrial carcinoma.

26 October 2017

1 reference

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Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function

26 October 2017

1 reference

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

26 October 2017

1 reference

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The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells

26 October 2017

1 reference

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Biliary excretion and intestinal metabolism of progesterone and estrogens in man.

26 October 2017

1 reference

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The use of human skin fibroblasts to obtain potency estimates of drug binding to androgen receptors

26 October 2017

1 reference

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Estrogen, androgen, glucocorticoid, and progesterone receptors in progestin-induced regression of human breast cancer

26 October 2017

1 reference

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The role of progestins in the treatment of breast cancer

26 October 2017

1 reference

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Acute therapy with megestrol acetate decreases nuclear and cytosol androgen receptors in human BPH tissue

26 October 2017

1 reference

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Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity

26 October 2017

1 reference

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Hormonal therapy of human endometrial adenocarcinoma in a nude mouse model

26 October 2017

1 reference

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Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate

26 October 2017

1 reference

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Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells

26 October 2017

1 reference

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Androgenic activity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture

26 October 2017

1 reference

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Influence of progestins on serum hormone levels in postmenopausal women with advanced breast cancer--I. General findings

26 October 2017

1 reference

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Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Hepatocellular carcinoma. A worldwide problem and the major risk factors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

A New Treatment for Hirsutism

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Androgenic properties and adrenal depressant activity of megestrol acetate observed in castrated male rats

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Medroxyprogesterone Acetate for the Evaluation of Hypertestosteronism in Hirsute Women

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Hepatic adenoma in Fanconi anemia treated with oxymetholone

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Experimental studies on endocrine therapy for rat hepatocellular carcinoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Metabolism of megestrol acetate and related progesterone analogues by liver preparations in vitro

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Sex hormone imbalance in male alcoholic cirrhotic patients with and without hepatocellular carcinoma

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Apparent resistance in human endometrial carcinoma during combination treatment with tamoxifen and progestin may result from desensitization following downregulation of tumor progesterone receptor.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Progesterone: an overview and recent advances

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Gender disparity of hepatocellular carcinoma: the roles of sex hormones

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

1,3-Diaxially substituted trans-decalins: potential nonsteroidal human progesterone receptor inhibitors

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Progesterone metabolism; investigation of the products of metabolism with human liver in vitro

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

High-dose tamoxifen in the treatment of inoperable hepatocellular carcinoma: A multicenter randomized controlled trial

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Variant estrogen receptors and their role in liver disease.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Activation of c-Src gene product in hepatocellular carcinoma is highly correlated with the indices of early stage phenotype.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Age at menarche and age at menopause in relation to hepatocellular carcinoma in women

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Absorption and metabolism of oral progesterone.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Trastuzumab plus estrogen suppression as salvage treatment in a case of liver failure due to metastatic breast cancer

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581253

Role of reproductive factors in hepatocellular carcinoma: Impact on hepatitis B- and C-related risk

3 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155/2013/290575

Bioavailability of progesterone with different modes of administration

21 January 2018

1 reference

12 December 2020

The effect of several sex steroid hormones on the growth rate of three Morris hepatoma tumor lines

1 reference

12 December 2020

Clinicopathologic comparisons between estrogen receptor-positive and -negative hepatocellular carcinomas

1 reference

12 December 2020

Progesterone receptor in hepatocellular carcinoma. Correlation with androgen and estrogen receptors

1 reference

12 December 2020

Chemohormonal therapy of unresectable hepatocellular carcinoma

1 reference

12 December 2020

Hepatocellular carcinoma in alcoholic cirrhosis: is sex hormone imbalance a pathogenetic factor?

1 reference

12 December 2020

Type of estrogen receptor determines response to antiestrogen therapy

1 reference

12 December 2020

Phase II study of megestrol acetate in the treatment of hepatocellular carcinoma

1 reference

12 December 2020

Functionality of the progesterone receptor in ovarian cancer and its regulation by estrogen

1 reference

12 December 2020

Specific progesterone binding to a membrane protein and related nongenomic effects on Ca2 -fluxes in sperm

1 reference

12 December 2020

Epidemiology of hepatocellular carcinoma

1 reference

12 December 2020

The metabolism of progesterone by liver tissue in vitro

1 reference

12 December 2020

The extra-hepatic metabolism of progesterone in rats

1 reference

12 December 2020

The metabolism of progesterone to delta4-pregnen-20alpha-ol-3-one in eviscerated female rats

1 reference

12 December 2020

Identifiers

DOI

10.1155/2013/290575

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

23484104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23484104 AND SRC:MED&resulttype=core&format=json