Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone. (Q42157886)

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title

Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone (English)

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1

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Iveta Mrízová

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David H. Phillips

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Marie Stiborova

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Walter Meinl

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Simone Florian

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Eszter Nagy

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Frantisek Barta

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Marlies Thomann

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Annette M Krais

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Maggie Liu

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Meirion Richards

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Amin Mirza

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Klaus Kopka

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Hansruedi Glatt

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Heinz H Schmeiser

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publication date

24 August 2016

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21 March 2020

published in

Archives of Toxicology

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volume

91

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issue

4

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21 March 2020

page(s)

1957-1975

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Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

24 August 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy.

29 May 2018

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29 May 2018

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Use of genetically manipulated Salmonella typhimurium strains to evaluate the role of human sulfotransferases in the bioactivation of nitro- and aminotoluenes.

29 May 2018

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³²P-postlabeling analysis of DNA adducts.

17 August 2018

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Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2.

17 August 2018

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³²P-postlabeling analysis of DNA adducts

17 August 2018

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Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania.

17 August 2018

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ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues.

17 August 2018

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Altered tissue distribution of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adducts in mice transgenic for human sulfotransferases 1A1 and 1A2.

17 August 2018

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Constitutive expression of bioactivating enzymes in normal human prostate suggests a capability to activate pro-carcinogens to DNA-damaging metabolites.

17 August 2018

1 reference

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Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.

17 August 2018

1 reference

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Investigation of the metabolism and reductive activation of carcinogenic aristolochic acids in rats.

17 August 2018

1 reference

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Tissue distribution and ontogeny of sulfotransferase enzymes in mice

17 August 2018

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Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine

17 August 2018

1 reference

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Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

17 August 2018

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Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

17 August 2018

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Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer?

17 August 2018

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Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by NADPH : cytochrome P450 reductase form adducts found in DNA of patients with Chinese herbs nephropathy.

17 August 2018

1 reference

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Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)

17 August 2018

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Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy

17 August 2018

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Crossref

https://api.crossref.org/works/10.1007/S00204-016-1808-6

32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy

21 January 2018

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12 December 2020

Study of the phase I and phase II metabolism of nephrotoxin aristolochic acid by liquid chromatography/tandem mass spectrometry

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12 December 2020

Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases

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12 December 2020

The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases

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12 December 2020

Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats

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A simple colorimetric assay for phenotyping the major human thermostable phenol sulfotransferase (SULT1A1) using platelet cytosols

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The carcinogen 1-methylpyrene forms benzylic DNA adducts in mouse and rat tissues in vivo via a reactive sulphuric acid ester

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Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy

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12 December 2020

10.1007/S00204-016-1808-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557898 AND SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557898 AND SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

27557898

1 reference