Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI (Q42141797)

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18 January 2020

title

Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI (English)

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18 January 2020

5

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18 January 2020

author name string

Dhanalakshmi Chinnasamy

1

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18 January 2020

Michael D Milsom

2

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18 January 2020

James Shaffer

3

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18 January 2020

James Neuenfeldt

4

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18 January 2020

Geoffrey P Margison

6

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18 January 2020

Leslie J Fairbairn

7

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18 January 2020

Nachimuthu Chinnasamy

8

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18 January 2020

publication date

15 March 2006

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18 January 2020

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18 January 2020

volume

3

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18 January 2020

page(s)

14

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Stable antibody expression at therapeutic levels using the 2A peptide

18 January 2020

cites work

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29 May 2018

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Lentivirus-mediated expression of mutant MGMTP140K protects human CD34 cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide

29 May 2018

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29 May 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

29 May 2018

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Correction of a Rat Model of Parkinson's Disease by Coexpression of Tyrosine Hydroxylase and Aromatic Amino Acid Decarboxylase from a Helper Virus-Free Herpes Simplex Virus Type 1 Vector

29 May 2018

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A multigene lentiviral vector system based on differential splicing.

29 May 2018

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High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34 cells, but impairs lymphomyeloid differentiation

29 May 2018

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Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs

29 May 2018

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Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

29 May 2018

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Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

29 May 2018

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Development of multigene and regulated lentivirus vectors

29 May 2018

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Tricistronic and tetracistronic retroviral vectors for gene transfer

29 May 2018

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O6-alkylguanine-DNA alkyltransferase assay.

29 May 2018

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Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage- colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses

29 May 2018

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Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins.

29 May 2018

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IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

29 May 2018

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Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy

29 May 2018

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Co-Expression of Human Adenosine Deaminase and Multidrug Resistance Using a Bicistronic Retroviral Vector

29 May 2018

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Immunohistological examination of the inter- and intracellular distribution of O6-alkylguanine DNA-alkyltransferase in human liver and melanoma

29 May 2018

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Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

29 May 2018

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Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV infected patients grouped according to CD4 count and viral load

17 August 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

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Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells

17 August 2018

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Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells

17 August 2018

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Production of human clotting Factor IX without toxicity in mice after vascular delivery of a lentiviral vector

17 August 2018

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Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons

17 August 2018

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Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy

17 August 2018

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Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors

17 August 2018

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Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice. Nonobese diabetic/severe combined immunodeficient

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16539700

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeting of proteins derived from self-processing polyproteins containing multiple signal sequences

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16539700

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1743-422X-3-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16539700 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 January 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1743-422x-3-14

1 reference

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18 January 2020

PubMed publication ID

16539700

1 reference