Kif2C minimal functional domain has unusual nucleotide binding properties that are adapted to microtubule depolymerization. (Q42141431)

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25 January 2020

title

Kif2C minimal functional domain has unusual nucleotide binding properties that are adapted to microtubule depolymerization (English)

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25 January 2020

5

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25 January 2020

author name string

Weiyi Wang

1

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25 January 2020

Qiyang Jiang

2

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25 January 2020

Manuela Argentini

3

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25 January 2020

David Cornu

4

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25 January 2020

Marcel Knossow

6

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25 January 2020

Chunguang Wang

7

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25 January 2020

language of work or name

English

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publication date

8 March 2012

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Journal of Biological Chemistry

25 January 2020

published in

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25 January 2020

volume

287

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25 January 2020

issue

18

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25 January 2020

page(s)

15143-15153

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The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.

25 January 2020

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Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.

29 May 2018

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TIP150 interacts with and targets MCAK at the microtubule plus ends

29 May 2018

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A kinesin-13 mutant catalytically depolymerizes microtubules in ADP

29 May 2018

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Structure of the Kinesin13-Microtubule Ring Complex

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29 May 2018

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29 May 2018

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29 May 2018

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Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK

29 May 2018

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N-terminal stathmin-like peptides bind tubulin and impede microtubule assembly

29 May 2018

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A standardized kinesin nomenclature

29 May 2018

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29 May 2018

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29 May 2018

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A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops

29 May 2018

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Kinesin walks hand-over-hand

29 May 2018

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Kinesin moves by an asymmetric hand-over-hand mechanism

29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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A structural change in the kinesin motor protein that drives motility

29 May 2018

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29 May 2018

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Coupling of kinesin steps to ATP hydrolysis

29 May 2018

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Kinesin hydrolyses one ATP per 8-nm step

29 May 2018

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Chemomechanical cycle of kinesin differs from that of myosin.

29 May 2018

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29 May 2018

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Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis

29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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17 August 2018

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Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer

17 August 2018

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Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension

17 August 2018

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17 August 2018

1 reference

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Kin I kinesins are microtubule-destabilizing enzymes

17 August 2018

1 reference

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Kinesin takes one 8-nm step for each ATP that it hydrolyzes

17 August 2018

1 reference

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Highly processive microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains

17 August 2018

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Crossref

https://api.crossref.org/works/10.1074/JBC.M111.317859

Regulation of ncd by the oligomeric state of tubulin

21 January 2018

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12 December 2020

Microtubule structure at 8 A resolution

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12 December 2020

Influence of the composition of commercial sodium dodecyl sulfate preparations on the separation of α- and β-tubulin during polyacrylamide gel electrophoresis

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12 December 2020

Weak and strong states of kinesin and ncd

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12 December 2020

Fluorescence polarization/anisotropy approaches to study protein-ligand interactions: effects of errors and uncertainties

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12 December 2020

Insight into the GTPase activity of tubulin from complexes with stathmin-like domains

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12 December 2020

Identifiers

DOI

10.1074/JBC.M111.317859

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403406 AND SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403406 AND SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

22403406

1 reference