Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-activated receptors PPARalpha and PPARdelta (Q42111464)

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scientific article published on 12 August 2008

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English	Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-activated receptors PPARalpha and PPARdelta	scientific article published on 12 August 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-activated receptors PPARalpha and PPARdelta (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

author name string

Pascal J H Smeets

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Birgit E J Teunissen

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Anna Planavila

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Heleen de Vogel-van den Bosch

4

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Peter H M Willemsen

5

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Ger J van der Vusse

6

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Marc van Bilsen

7

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

language of work or name

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publication date

12 August 2008

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Europe PubMed Central

PMC publication ID

16 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 October 2017

283

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Europe PubMed Central

PMC publication ID

16 October 2017

43

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

29109-29118

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Peroxisome proliferator-activated receptors and inflammation: take it to heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Regulating the regulator: NF-kappaB signaling in heart

1 reference

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29 May 2018

Systemic inflammation in heart failure--the whys and wherefores

1 reference

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29 May 2018

Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

NADH oxidase signaling induces cyclooxygenase-2 expression during lipopolysaccharide stimulation in cardiomyocytes

1 reference

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29 May 2018

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

1 reference

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29 May 2018

Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation

1 reference

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29 May 2018

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Peroxisome proliferator-activated receptors: lipid binding proteins controling gene expression

1 reference

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29 May 2018

Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

29 May 2018

Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Cardiomyocytic apoptosis following global cardiac ischemia and reperfusion can be attenuated by peroxisome proliferator-activated receptor alpha but not gamma activators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo

1 reference

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17 August 2018

Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha

1 reference

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17 August 2018

Blockade of NF-kappaB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

PPAR-gamma modulates allergic inflammation through up-regulation of PTEN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Inhibition of NF-kappaB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

NF-kappaB activation is required for the development of cardiac hypertrophy in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Ligands of the peroxisome proliferator-activated receptor-PPAR-a reduce myocardial infarct size.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662011

17 August 2018

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

1 reference

https://api.crossref.org/works/10.1074/JBC.M802143200

21 January 2018

Induction of IκBα Expression as a Mechanism Contributing to the Anti-inflammatory Activities of Peroxisome Proliferator-activated Receptor-α Activators

1 reference

https://api.crossref.org/works/10.1074/JBC.M802143200

21 January 2018

Cardiac hypertrophy is enhanced in PPAR -/- mice in response to chronic pressure overload

1 reference

https://api.crossref.org/works/10.1074/JBC.M802143200

21 January 2018

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha provokes a hypertrophic growth response in adult cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Left ventricular hypertrophy in mice with a cardiac-specific overexpression of interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARdelta activation normalizes cardiac substrate metabolism and reduces right ventricular hypertrophy in congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-inflammatory Cytokines Stimulate Mitogen-activated Protein Kinase Subfamilies, Increase Phosphorylation of c-Jun and ATF2 and Upregulate c-Jun Protein in Neonatal Rat Ventricular Myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18701451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M802143200

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

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