Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance (Q42108254)

16 October 2017

Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance (English)

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16 October 2017

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7

Nobutaka Hattori

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16 October 2017

Zhihao Wu

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16 October 2017

Tomoyo Sawada

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16 October 2017

Kahori Shiba

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16 October 2017

Song Liu

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16 October 2017

Tomoko Kanao

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16 October 2017

Ryosuke Takahashi

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16 October 2017

Yuzuru Imai

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16 October 2017

Bingwei Lu

9

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16 October 2017

1 January 2013

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157-162

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describes a project that uses

16 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3566308/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

29 May 2018

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Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development

29 May 2018

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Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria

29 May 2018

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Mitochondrial quality control: a matter of life and death for neurons

29 May 2018

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The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants

29 May 2018

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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

29 May 2018

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29 May 2018

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An emerging role for TOR signaling in mammalian tissue and stem cell physiology

29 May 2018

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Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

29 May 2018

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Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression.

29 May 2018

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Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

29 May 2018

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Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control

29 May 2018

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A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2

29 May 2018

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mTOR: from growth signal integration to cancer, diabetes and ageing

29 May 2018

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Reduction of Protein Translation and Activation of Autophagy Protect against PINK1 Pathogenesis in Drosophila melanogaster

29 May 2018

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Regulation of cell shape, wing hair initiation and the actin cytoskeleton by Trc/Fry and Wts/Mats complexes

29 May 2018

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Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

29 May 2018

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

29 May 2018

1 reference

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The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway

29 May 2018

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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

29 May 2018

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Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

29 May 2018

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Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth

29 May 2018

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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

29 May 2018

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

29 May 2018

1 reference

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

29 May 2018

1 reference

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Interactions of mitochondria with the actin cytoskeleton

29 May 2018

1 reference

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NDR kinases regulate essential cell processes from yeast to humans

29 May 2018

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TOR signaling in growth and metabolism

29 May 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

29 May 2018

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

29 May 2018

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

29 May 2018

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The tricornered gene, which is required for the integrity of epidermal cell extensions, encodes the Drosophila nuclear DBF2-related kinase.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566308

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

29 May 2018

1 reference

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The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance

29 May 2018

1 reference

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Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation

17 August 2018

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Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons.

17 August 2018

1 reference

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17 August 2018

Identifiers

DOI

10.1101/GAD.203406.112

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

23348839

1 reference