Roles of human POLD1 and POLD3 in genome stability (Q42104410)

16 October 2017

Roles of human POLD1 and POLD3 in genome stability (English)

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16 October 2017

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16 October 2017

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16 October 2017

Emanuela Tumini

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author name string

Carmen Pérez -Calero

series ordinal

3

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16 October 2017

language of work or name

English

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publication date

15 December 2016

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16 October 2017

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16 October 2017

38873

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describes a project that uses

16 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5156928/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

POLD3 Is Haploinsufficient for DNA Replication in Mice.

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A panoply of errors: polymerase proofreading domain mutations in cancer

29 May 2018

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Replication stress activates DNA repair synthesis in mitosis.

29 May 2018

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The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

29 May 2018

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The Fanconi Anemia Pathway Protects Genome Integrity from R-loops

29 May 2018

1 reference

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R loops: new modulators of genome dynamics and function

29 May 2018

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Human POLD1 modulates cell cycle progression and DNA damage repair

29 May 2018

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Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.

29 May 2018

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Eukaryotic DNA polymerase ζ

29 May 2018

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BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair

29 May 2018

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The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ.

29 May 2018

1 reference

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Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability

29 May 2018

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New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis

29 May 2018

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Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass

29 May 2018

1 reference

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Break-induced replication repair of damaged forks induces genomic duplications in human cells.

29 May 2018

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The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression

29 May 2018

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R loops are linked to histone H3 S10 phosphorylation and chromatin condensation

29 May 2018

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Causes of genome instability

29 May 2018

1 reference

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Break-induced replication: functions and molecular mechanism

29 May 2018

1 reference

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End-joining, translocations and cancer

29 May 2018

1 reference

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Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells

29 May 2018

1 reference

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Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases

29 May 2018

1 reference

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A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis

29 May 2018

1 reference

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DNA polymerase delta in DNA replication and genome maintenance

29 May 2018

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Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells

29 May 2018

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Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ

29 May 2018

1 reference

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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

29 May 2018

1 reference

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Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing.

29 May 2018

1 reference

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DNA Polymerase δ and ζ Switch by Sharing Accessory Subunits of DNA Polymerase δ

29 May 2018

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R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters

29 May 2018

1 reference

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Genome instability and transcription elongation impairment in human cells depleted of THO/TREX

29 May 2018

1 reference

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Inhibition of REV3 expression induces persistent DNA damage and growth arrest in cancer cells

29 May 2018

1 reference

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Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

29 May 2018

1 reference

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Studies on Human DNA Polymerase ϵ and GINS Complex and Their Role in DNA Replication

29 May 2018

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Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

29 May 2018

1 reference

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Camptothecin induces DNA strand breaks and is cytotoxic in stimulated normal lymphocytes

29 May 2018

1 reference

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Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer.

29 May 2018

1 reference

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Mechanisms of chromosomal instability.

29 May 2018

1 reference

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Functional genomic screens identify CINP as a genome maintenance protein

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Division of labor at the eukaryotic replication fork

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Sister chromatid exchange

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

DNA polymerase zeta (pol zeta) in higher eukaryotes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Break-induced replication and telomerase-independent telomere maintenance require Pol32.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Replication fork stalling at natural impediments

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA).

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Eukaryotic DNA Polymerases

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Phosphorylation of the p68 subunit of Pol δ acts as a molecular switch to regulate its interaction with PCNA.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Characterization of the Two Small Subunits of Saccharomyces cerevisiae DNA Polymerase δ

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5156928

Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27974823

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP38873

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

27974823

1 reference