Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition. (Q42044394)

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25 January 2020

title

Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition (English)

1 reference

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25 January 2020

0 references

1

1 reference

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25 January 2020

Beerend P. Hierck

8

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25 January 2020

author name string

Padmini P S J Khedoe

2

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25 January 2020

Marie-José T H Goumans

3

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25 January 2020

Bradley K Yoder

4

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25 January 2020

Surya M Nauli

5

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25 January 2020

Peter ten Dijke

6

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25 January 2020

Robert E Poelmann

7

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25 January 2020

publication date

10 March 2011

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25 January 2020

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25 January 2020

volume

108

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25 January 2020

issue

9

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25 January 2020

page(s)

1093-1101

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Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells

25 January 2020

cites work

1 reference

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Biomarkers for epithelial-mesenchymal transitions

5 June 2018

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Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis?

5 June 2018

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Roles of TGFbeta and BMP during valvulo-septal endocardial cushion formation

5 June 2018

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Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis

5 June 2018

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Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury

5 June 2018

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

5 June 2018

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Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

5 June 2018

1 reference

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The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous ligation model

5 June 2018

1 reference

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

5 June 2018

1 reference

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Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart

5 June 2018

1 reference

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The roles of cilia in developmental disorders and disease

5 June 2018

1 reference

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Overview of structure and function of mammalian cilia

5 June 2018

1 reference

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The primary cilium as the cell's antenna: signaling at a sensory organelle

5 June 2018

1 reference

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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

5 June 2018

1 reference

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Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

5 June 2018

1 reference

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Primary cilia of human endothelial cells disassemble under laminar shear stress

5 June 2018

1 reference

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Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

5 June 2018

1 reference

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Cilia are at the heart of vertebrate left-right asymmetry

5 June 2018

1 reference

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Removal of the MDCK cell primary cilium abolishes flow sensing

5 June 2018

1 reference

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

5 June 2018

1 reference

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5 June 2018

Intraflagellar transport

1 reference

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Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)

5 June 2018

1 reference

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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

5 June 2018

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DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells

5 June 2018

1 reference

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Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP).

5 June 2018

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Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

5 June 2018

1 reference

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Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

5 June 2018

1 reference

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Robin Fåhraeus: evolution of his concepts in cardiovascular physiology

5 June 2018

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Spectrum of heart malformations in mice with situs solitus, situs inversus, and associated visceral heterotaxy

5 June 2018

1 reference

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Fluid shear stress and inner curvature remodeling of the embryonic heart. Choosing the right lane!

5 June 2018

1 reference

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Kruppel-like factor 4 regulates endothelial inflammation.

17 August 2018

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In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart.

17 August 2018

1 reference

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Endothelial dysfunction and increased carotid intima-media thickness in patients with autosomal dominant polycystic kidney disease

17 August 2018

1 reference

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17 August 2018

1 reference

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Deciphering the Endothelial Shear Stress Sensor

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094764

Primary cilia sensitize endothelial cells for fluid shear stress

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094764

Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094764

Monocilia on chicken embryonic endocardium in low shear stress areas

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094764

KLF4: a novel target for the treatment of atherosclerosis

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21393577

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21393577

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/CIRCRESAHA.110.231860

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21393577 AND SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21393577 AND SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

21393577

1 reference