Tolerability and pharmacokinetics of inhaled bimosiamose disodium in healthy males. (Q42010395)

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21 December 2019

title

Tolerability and pharmacokinetics of inhaled bimosiamose disodium in healthy males (English)

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8

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7

Bernd Jilma

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21 December 2019

author name string

Michael Meyer

1

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Kai-Michael Beeh

2

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Jutta Beier

3

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Diana Beyer

4

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Ewald Aydt

5

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Rainer Zahlten

6

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language of work or name

English

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publication date

20 September 2006

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British Journal of Clinical Pharmacology

21 December 2019

published in

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volume

63

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issue

4

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page(s)

451-458

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Selectin antagonists : therapeutic potential in asthma and COPD.

21 December 2019

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Inhibition of adhesion of human neutrophils and eosinophils to P-selectin by the sialyl Lewis antagonist TBC1269: preferential activity against neutrophil adhesion in vitro

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Novel Synthetic Inhibitors of Selectin-Mediated Cell Adhesion: Synthesis of 1,6-Bis[3-(3-carboxymethylphenyl)-4-(2-α-d-mannopyranosyloxy)phenyl]hexane (TBC1269)

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Physiochemical properties, safety and pharmacokinetics of bimosiamose disodium after intravenous administration.

5 June 2018

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Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial.

17 August 2018

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The Effect of Breathing Pattern on Nebulizer Drug Delivery

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A selectin inhibitor decreases neutrophil infiltration during acute Mannheimia haemolytica pneumonia

17 August 2018

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Multiple selectin blockade with a small-molecule selectin inhibitor does not affect survival after a second inflammatory challenge with nonlethal LPS.

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12 December 2020

The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma

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Small-Molecule Selectin Inhibitor Protects Against Liver Inflammatory Response After Ischemia and Reperfusion

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Determinants of bronchial responsiveness in the European Community Respiratory Health Survey in Italy: evidence of an independent role of atopy, total serum IgE levels, and asthma symptoms

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Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep

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Inhalation therapy in asthma: nebulizer or pressurized metered-dose inhaler with holding chamber? In vivo comparison of lung deposition in children

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An in vitro analysis of the output of salbutamol from different nebulizers

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10.1111/J.1365-2125.2006.02775.X

Identifiers

DOI

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21 December 2019

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21 December 2019

PubMed publication ID

17067318

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