Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma (Q41955454)

14 October 2017

Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma (English)

1 reference

14 October 2017

6

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1 June 2020

David H. Munn

8

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1 June 2020

9

David L Bartlett

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1 June 2020

author name string

Yuan Hong

1

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1 June 2020

Yibing Peng

2

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1 June 2020

Z Sheng Guo

3

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1 June 2020

Jose Guevara-Patino

4

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1 June 2020

Junfeng Pang

5

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1 June 2020

Nahid F Mivechi

7

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1 June 2020

Yukai He

10

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1 June 2020

language of work or name

English

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publication date

18 February 2014

1 reference

14 October 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122861 AND SRC:MED&resulttype=core&format=json

1 June 2020

volume

59

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1 June 2020

issue

4

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1 June 2020

page(s)

1448-1458

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Population-attributable fractions of risk factors for hepatocellular carcinoma in the United States

1 June 2020

cites work

1 reference

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Value of α-fetoprotein in association with clinicopathological features of hepatocellular carcinoma

5 June 2018

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Targeting lentiviral vectors for cancer immunotherapy

5 June 2018

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T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

5 June 2018

1 reference

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Immunotherapy of hepatocellular carcinoma: Unique challenges and clinical opportunities

5 June 2018

1 reference

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The immunogenicity of the tumor-associated antigen α-fetoprotein is enhanced by a fusion with a transmembrane domain.

5 June 2018

1 reference

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Lentivector Prime and Vaccinia Virus Vector Boost Generate High-Quality CD8 Memory T Cells and Prevent Autochthonous Mouse Melanoma

5 June 2018

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Heat Shock Transcription Factor 1 Is a Key Determinant of HCC Development by Regulating Hepatic Steatosis and Metabolic Syndrome

5 June 2018

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Alpha fetoprotein is more than a hepatocellular cancer biomarker: from spontaneous immune response in cancer patients to the development of an AFP-based cancer vaccine

5 June 2018

1 reference

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One-step simple assay to determine antigen-specific cytotoxic activities by single-color flow cytometry

5 June 2018

1 reference

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Lentivector expressing HBsAg and immunoglobulin Fc fusion antigen induces potent immune responses and results in seroconversion in HBsAg transgenic mice

5 June 2018

1 reference

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

5 June 2018

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Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability.

5 June 2018

1 reference

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Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

5 June 2018

1 reference

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Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100

5 June 2018

1 reference

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Lentivector immunization stimulates potent CD8 T cell responses against melanoma self-antigen tyrosinase-related protein 1 and generates antitumor immunity in mice.

5 June 2018

1 reference

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Immunotherapy of murine hepatocellular carcinoma by alpha-fetoprotein DNA vaccination combined with adenovirus-mediated chemokine and cytokine expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen

5 June 2018

1 reference

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Lentivirus as a potent and mechanistically distinct vector for genetic immunization

5 June 2018

1 reference

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A DNA vaccine against chimeric AFP enhanced by HSP70 suppresses growth of hepatocellular carcinoma

5 June 2018

1 reference

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Skin-derived dendritic cells induce potent CD8( ) T cell immunity in recombinant lentivector-mediated genetic immunization

5 June 2018

1 reference

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Optimization of a self antigen for presentation of multiple epitopes in cancer immunity

5 June 2018

1 reference

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Epidemiology of hepatitis C virus (HCV) infection

5 June 2018

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Introduction to chronic hepatitis B infection

5 June 2018

1 reference

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The enhanced tumor selectivity of an oncolytic vaccinia lacking the host range and antiapoptosis genes SPI-1 and SPI-2.

5 June 2018

1 reference

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Quantification and characterization of specific T-cells by antigen-specific cytokine production using ELISPOT assay or intracellular cytokine staining

5 June 2018

1 reference

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In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8( ) T cell responses

5 June 2018

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Positive and negative selection of T cells

5 June 2018

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T cell responses to HLA-A*0201-restricted peptides derived from human alpha fetoprotein

5 June 2018

1 reference

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Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia

5 June 2018

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Generation of human T-cell responses to an HLA-A2.1-restricted peptide epitope derived from alpha-fetoprotein.

5 June 2018

1 reference

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Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma

5 June 2018

1 reference

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Heteroclitic immunization induces tumor immunity

5 June 2018

1 reference

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gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand

5 June 2018

1 reference

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Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides

5 June 2018

1 reference

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A Comparison of Prognosis between Patients with Hepatitis B and C Virus‐related Hepatocellular Carcinoma Undergoing Resection Surgery

18 August 2018

1 reference

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Decreased incidence of hepatocellular carcinoma in hepatitis B vaccinees: a 20-year follow-up study.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

T-cell responses to HLA-A*0201 immunodominant peptides derived from alpha-fetoprotein in patients with hepatocellular cancer.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

alpha-Fetoprotein-specific tumor immunity induced by plasmid prime-adenovirus boost genetic vaccination

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

Fine specificity analysis of an HLA-A2.1-restricted immunodominant T cell epitope derived from human alpha-fetoprotein

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

Mouse alpha-fetoprotein-specific DNA-based immunotherapy of hepatocellular carcinoma leads to tumor regression in mice

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

Genetic immunization is a simple method for eliciting an immune response

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151349

AFP-specific immunotherapy impairs growth of autochthonous hepatocellular carcinoma in mice

18 August 2018

1 reference

12 December 2020

[Inhibitory effects of human AFP-derived peptide-pulsed dendritic cells on mouse hepatocellular carcinoma]

1 reference

12 December 2020

Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex

1 reference

12 December 2020

A Phase I/II Trial Testing Immunization of Hepatocellular Carcinoma Patients with Dendritic Cells Pulsed with Four -Fetoprotein Peptides

1 reference

12 December 2020

Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability

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12 December 2020

Identifiers

DOI

10.1002/HEP.26893

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122861 AND SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

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1 June 2020

PubMed publication ID

24122861

1 reference