Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains (Q41929666)

14 October 2017

Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains (English)

1 reference

14 October 2017

6

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31 May 2020

author name string

Kai-Cheng Hsu

1

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31 May 2020

Hui-Chen Hung

2

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31 May 2020

Wei-Chun HuangFu

3

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31 May 2020

Tzu-Ying Sung

4

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31 May 2020

Tony Eight Lin

5

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31 May 2020

I-Jung Chen

7

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31 May 2020

Nikhil Pathak

8

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31 May 2020

John T-A Hsu

9

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31 May 2020

Jinn-Moon Yang

10

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31 May 2020

language of work or name

English

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publication date

26 September 2017

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14 October 2017

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31 May 2020

volume

7

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31 May 2020

issue

1

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31 May 2020

page(s)

12336

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Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

26 September 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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5 June 2018

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5 June 2018

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Targeting a cluster of arginine residues of neuraminidase to avoid oseltamivir resistance in influenza A (H1N1): a theoretical study.

5 June 2018

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Neuraminidase mutations conferring resistance to laninamivir lead to faster drug binding and dissociation

5 June 2018

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5 June 2018

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Epistatic interactions between neuraminidase mutations facilitated the emergence of the oseltamivir-resistant H1N1 influenza viruses

5 June 2018

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Multiple influenza A (H3N2) mutations conferring resistance to neuraminidase inhibitors in a bone marrow transplant recipient

5 June 2018

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Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.

5 June 2018

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5 June 2018

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Parallel screening of wild-type and drug-resistant targets for anti-resistance neuraminidase inhibitors

5 June 2018

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Outside-binding site mutations modify the active site's shapes in neuraminidase from influenza A H1N1.

5 June 2018

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I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y

5 June 2018

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Long time scale GPU dynamics reveal the mechanism of drug resistance of the dual mutant I223R/H275Y neuraminidase from H1N1-2009 influenza virus

5 June 2018

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Influenza neuraminidase

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Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition

5 June 2018

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iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis

5 June 2018

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Spatio-temporal data comparisons for global highly pathogenic avian influenza (HPAI) H5N1 outbreaks

5 June 2018

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Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

5 June 2018

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SiMMap: a web server for inferring site-moiety map to recognize interaction preferences between protein pockets and compound moieties

5 June 2018

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5 June 2018

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In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses.

5 June 2018

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Safety of neuraminidase inhibitors against novel influenza A (H1N1) in pregnant and breastfeeding women

5 June 2018

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A novel small-molecule inhibitor of the avian influenza H5N1 virus determined through computational screening against the neuraminidase.

5 June 2018

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Aurintricarboxylic acid inhibits influenza virus neuraminidase

5 June 2018

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CS-8958, a prodrug of the new neuraminidase inhibitor R-125489, shows long-acting anti-influenza virus activity

5 June 2018

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Structural Characterization of the 1918 Influenza Virus H1N1 Neuraminidase

5 June 2018

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Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase.

5 June 2018

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Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

5 June 2018

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Recent progress in rational drug design of neuraminidase inhibitors

5 June 2018

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Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.

5 June 2018

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Molecular regulation of angiogenesis and lymphangiogenesis

5 June 2018

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Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.

5 June 2018

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The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.

5 June 2018

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Importance of neuraminidase active-site residues to the neuraminidase inhibitor resistance of influenza viruses

5 June 2018

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Avian influenza virus: the threat of a pandemic.

5 June 2018

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Optimization of small molecule drugs binding to highly polar target sites: lessons from the discovery and development of neuraminidase inhibitors

5 June 2018

1 reference

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Oseltamivir resistance during treatment of influenza A (H5N1) infection

5 June 2018

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Oseltamivir resistance--disabling our influenza defenses

5 June 2018

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The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

5 June 2018

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Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir

5 June 2018

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Immunological effects of the orally administered neuraminidase inhibitor oseltamivir in influenza virus-infected and uninfected mice

5 June 2018

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Hydrophobic benzoic acids as inhibitors of influenza neuraminidase

5 June 2018

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Site-directed mutagenesis of catalytic residues of influenza virus neuraminidase as an aid to drug design

5 June 2018

1 reference

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A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activity

5 June 2018

1 reference

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Protein structure alignment by incremental combinatorial extension (CE) of the optimal path

5 June 2018

1 reference

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Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors

5 June 2018

1 reference

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Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases

5 June 2018

1 reference

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Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5615050

Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-alpha-D-N-acetylneuraminate) substrate

5 June 2018

1 reference

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WHO downgrades oseltamivir on drugs list after reviewing evidence

5 June 2018

1 reference

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Emergence of a Multidrug-Resistant Pandemic Influenza A (H1N1) Virus

18 August 2018

1 reference

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Recovery of a Multidrug‐Resistant Strain of Pandemic Influenza A 2009 (H1N1) Virus Carrying a Dual H275Y/I223R Mutation from a Child after Prolonged Treatment with Oseltamivir

18 August 2018

1 reference

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Rational design of Tamiflu derivatives targeting at the open conformation of neuraminidase subtype 1.

18 August 2018

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Source of oseltamivir resistance in avian influenza H5N1 virus with the H274Y mutation

18 August 2018

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Comparative binding energy (COMBINE) analysis of influenza neuraminidase-inhibitor complexes.

18 August 2018

1 reference

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Inhibition of influenza and parainfluenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA).

18 August 2018

1 reference

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Comparison of Automatic Three-Dimensional Model Builders Using 639 X-ray Structures

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/S41598-017-12101-3

Structural biology: Antiviral drugs fit for a purpose

21 January 2018

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10.1038/S41598-017-12101-3

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28951584 AND SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28951584 AND SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

28951584

1 reference