Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases (Q41928193)

14 October 2017

Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases (English)

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14 October 2017

Valerie Anne Galton

1

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14 October 2017

Mark J Schneider

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2

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14 October 2017

Ann S Clark

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3

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14 October 2017

Donald L St Germain

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4

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14 October 2017

language of work or name

English

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publication date

5 February 2009

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14 October 2017

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14 October 2017

150

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14 October 2017

6

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14 October 2017

2957-2963

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Mutations in SECISBP2 result in abnormal thyroid hormone metabolism

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Hepatic deiodinase activity is dispensable for the maintenance of normal circulating thyroid hormone levels in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Perspectives in the study of thyroid hormone action on brain development and function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Thyroid hormone action in neural development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

The thyroid gland is a major source of circulating T3 in the rat.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Activation and inactivation of thyroid hormone by type I iodothyronine deiodinase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

The Deiodination of the Iodothyronines and of Their Derivatives in Man

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Comparative study of pituitary-thyroid hormone economy in fasting and hypothyroid rats

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

The cDNA for the type I iodothyronine 5‘-deiodinase encodes an enzyme manifesting both high Km and low Km activity. Evidence that rat liver and kidney contain a single enzyme which converts thyroxine to 3,5,3‘-triiodothyronine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Variations in the response of the thyroid gland of the rat to different low-iodine diets: correlation with iodine content of diet

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Thyroid hormone homeostasis and action in the type 2 deiodinase-deficient rodent brain during development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Targeted disruption of the type 1 selenodeiodinase gene (Dio1) results in marked changes in thyroid hormone economy in mice

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Comparative kinetic characterization of rat thyroid iodotyrosine dehalogenase and iodothyronine deiodinase type 1.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Direct measurement of the contributions of type I and type II 5'-deiodinases to whole body steady state 3,5,3'-triiodothyronine production from thyroxine in the rat.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

The effects of congenital hypothyroidism using the hyt/hyt mouse on locomotor activity and learned behavior

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Human Cord Blood Concentrations of Thyrotropin, Thyroglobulin, and Iodothyronines after Maternal Administration of Thyrotropin-Releasing Hormone*

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2689801

Thyroid hormone secretion rates: response to endogenous and exogenous TSH in man during surgery

2 December 2018

1 reference

12 December 2020

Metabolism of triiodothyroacetic acid (TA3) in rat liver. II. Deiodination and conjugation of TA3 by rat hepatocytes and in rats in vivo

1 reference

12 December 2020

Changes in Plasma Thyroxine, Triiodothyronine, and TSH During Adaptation to Iodine Deficiency in the Rat

1 reference

12 December 2020

Effects of intrathyroidal metabolism of thyroxine on thyroid hormone secretion: increased degradation of thyroxine in mouse thyroids stimulated chronically with thyrotrophin

1 reference

12 December 2020

Phenolic and nonphenolic ring iodothyronine deiodinases from rat thyroid gland

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12 December 2020

Sequential deiodination of thyroxine in human thyroid gland.

1 reference

12 December 2020

Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations

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12 December 2020

Specific nuclear triiodothyronine binding sites in rat liver and kidney

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12 December 2020

Effects of prolonged administration of thyrotrophin on serum concentration, release and synthesis of thyroid hormones in mice

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12 December 2020

Sources of circulating 3,5,3'-triiodothyronine in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases

1 reference

12 December 2020

Thyroid hormone metabolism and the source of plasma triiodothyronine in 2-week-old rats: effects of thyroid status

1 reference

12 December 2020

Deiodination of the iodinated amino acids

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12 December 2020

Identifiers

DOI

10.1210/EN.2008-1572

1 reference

14 October 2017

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14 October 2017

PubMed publication ID

19196796

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