A Screen for Protein-Protein Interactions in Live Mycobacteria Reveals a Functional Link between the Virulence-Associated Lipid Transporter LprG and the Mycolyltransferase Antigen 85A. (Q41880977)

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scientific article published on 9 March 2017

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English	A Screen for Protein-Protein Interactions in Live Mycobacteria Reveals a Functional Link between the Virulence-Associated Lipid Transporter LprG and the Mycolyltransferase Antigen 85A.	scientific article published on 9 March 2017

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5 April 2020

A Screen for Protein-Protein Interactions in Live Mycobacteria Reveals a Functional Link between the Virulence-Associated Lipid Transporter LprG and the Mycolyltransferase Antigen 85A (English)

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5 April 2020

protein-protein interaction

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Megan H Touchette

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Armand B Cognetta

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Benjamin Cravatt

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Jessica C Seeliger

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Keriann M. Backus

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Keriann M Backus

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Erik R Van Vlack

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Lu Bai

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Jia Kim

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Mary L Previti

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Dwight W Martin

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21 March 2017

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ACS Infectious Diseases

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336-348

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11 June 2022

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Transport of outer membrane lipids in mycobacteria

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Spatially distinct and metabolically active membrane domain in mycobacteria

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Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis

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The Phyre2 web portal for protein modeling, prediction and analysis

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Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion

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Mycobacterium tuberculosis strains lacking surface lipid phthiocerol dimycocerosate are susceptible to killing by an early innate host response

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LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis

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Mycobacterium tuberculosis proteins involved in mycolic acid synthesis and transport localize dynamically to the old growing pole and septum

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Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export

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MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria

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Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

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SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis

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Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity.

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Recent advances in deciphering the contribution of Mycobacterium tuberculosis lipids to pathogenesis

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Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2

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10.1021/ACSINFECDIS.6B00179

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