Investigation of the metabolism of substance P at the blood-brain barrier using LC-MS/MS. (Q41864443)

13 October 2017

Investigation of the metabolism of substance P at the blood-brain barrier using LC-MS/MS. (English)

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13 October 2017

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Arvind K Chappa

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13 October 2017

Joshua D Cooper

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13 October 2017

Kenneth L Audus

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13 October 2017

Susan M Lunte

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13 October 2017

21 November 2006

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13 October 2017

7

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Journal of Pharmaceutical and Biomedical Analysis

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published in

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13 October 2017

43

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13 October 2017

4

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13 October 2017

1409-1415

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describes a project that uses

13 October 2017

liquid chromatography–mass spectrometry

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liquid chromatography-tandem mass spectrometry

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Neuroprotection in experimental stroke with targeted neurotrophins

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cites work

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Angiotensin peptides as neurotransmitters/neuromodulators in the dorsomedial medulla

5 June 2018

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Investigation of the metabolism of substance P at the blood-brain barrier using capillary electrophoresis with laser-induced fluorescence detection

5 June 2018

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Investigation of the metabolism of substance P in rat striatum by microdialysis sampling and capillary electrophoresis with laser-induced fluorescence detection

5 June 2018

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The N-terminal domain of substance P is required for complete homologous desensitization but not phosphorylation of the rat neurokinin-1 receptor

5 June 2018

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Electrospray and tandem mass spectrometry in biochemistry.

5 June 2018

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Is there a future for neuropeptide receptor ligands in the treatment of anxiety disorders?

5 June 2018

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Evaluation of capillary electrophoresis with post-column derivatization and laser-induced fluorescence detection for the determination of substance P and its metabolites

5 June 2018

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Evidence for modulatory effects of substance P fragments (1-4) and (8-11) on endogenous dopamine outflow in rat striatal slices

5 June 2018

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The 84-kDa form of human matrix metalloproteinase-9 degrades substance P and gelatin.

5 June 2018

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The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11.

5 June 2018

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Degradation of substance P by neurones and glial cells

5 June 2018

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Characteristics of aminopeptidase activity from bovine brain microvessel endothelium

5 June 2018

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Intranigral substance P modulation of striatal dopamine: interaction with N-terminal and C-terminal substance P fragments

5 June 2018

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Role of Substance P Amino Terminal Metabolites in Substance P-Induced Desensitization in Mice

5 June 2018

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Differential effects of C- and N-terminal substance P metabolites on the release of amino acid neurotransmitters from the spinal cord: potential role in nociception

5 June 2018

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Aminopeptidase P from rat brain. Purification and action on bioactive peptides

5 June 2018

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Endomorphins exit the brain by a saturable efflux system at the basolateral surface of cerebral endothelial cells

5 June 2018

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In vivo metabolism and clearance of substance P and co-expressed tachykinins in rat striatum

18 August 2018

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Injection of substance P (SP) N-terminal fragment SP(1-7) into the ventral tegmental area modulates the levels of nucleus accumbens dopamine and dihydroxyphenylacetic acid in male rats during morphine withdrawal

18 August 2018

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Neuronal nitric oxide synthase (nNOS) mRNA is down-regulated, and constitutive NOS enzymatic activity decreased, in thoracic dorsal root ganglia and spinal cord of the rat by a substance P N-terminal metabolite

18 August 2018

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Substance P fragments and striatal endogenous dopamine outflow: interaction with substance P.

18 August 2018

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Identification of substance P metabolites using a combination of reversed-phase high-performance liquid chromatography and capillary electrophoresis.

18 August 2018

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Leucine-enkephalin metabolism in brain microvessel endothelial cells

18 August 2018

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A new feature of angiotensin-converting enzyme in the brain: Hydrolysis of substance P

18 August 2018

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Substance K and substance P as possible endogenous substrates of angiotensin converting enzyme in the brain

18 August 2018

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Cleavage of substance P to an N-terminal tetrapeptide and a C-terminal heptapeptide by a post-proline cleaving enzyme from bovine brain

18 August 2018

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12 December 2020

Characterization of substance P(1-7) and (1-8) generating enzyme in human cerebrospinal fluid

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12 December 2020

Purification and characterization of a substance P-degrading endopeptidase from rat brain

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12 December 2020

The role of enzymatic processing in the biological actions of substance P

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12 December 2020

Inhibition of Hyperalgesia by Ablation of Lamina I Spinal Neurons Expressing the Substance P Receptor

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12 December 2020

10.1016/J.JPBA.2006.10.005

Identifiers

DOI

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13 October 2017

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13 October 2017

PubMed publication ID

17118606

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