The Murine Goblet Cell Protein mCLCA3 Is a Zinc-Dependent Metalloprotease with Autoproteolytic Activity (Q41864273)

13 October 2017

The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity (English)

1 reference

13 October 2017

The Murine Goblet Cell Protein mCLCA3 Is a Zinc-Dependent Metalloprotease with Autoproteolytic Activity (English)

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

17 December 2024

author name string

Lars Mundhenk

2

1 reference

13 October 2017

Matthias Kaup

3

1 reference

13 October 2017

Christoph Weise

4

1 reference

13 October 2017

Melanie K. Bothe

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22080371

17 December 2024

Achim D. Gruber

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22080371

17 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22080371

17 December 2024

publication date

9 November 2011

1 reference

full work available at URL

13 October 2017

https://europepmc.org/articles/pmc3887686?pdf=render

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22080371

https://europepmc.org/articles/PMC3887686

17 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22080371

https://europepmc.org/articles/PMC3887686?pdf=render

17 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22080371

https://doi.org/10.1007/s10059-011-0158-8

17 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22080371

http://link.springer.com/content/pdf/10.1007/s10059-011-0158-8.pdf

17 December 2024

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

http://link.springer.com/article/10.1007/s10059-011-0158-8/fulltext.html

17 December 2024

file format

HyperText Markup Language

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

https://api.elsevier.com/content/article/PII:S1016847823072527?httpAccept=text/xml

17 December 2024

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

https://api.elsevier.com/content/article/PII:S1016847823072527?httpAccept=text/plain

17 December 2024

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

http://link.springer.com/content/pdf/10.1007/s10059-011-0158-8

17 December 2024

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

17 December 2024

1 reference

13 October 2017

32

1 reference

13 October 2017

6

1 reference

13 October 2017

535-541

1 reference

Tissue and cellular expression patterns of porcine CFTR: similarities to and differences from human CFTR

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Genomic, tissue expression, and protein characterization of pCLCA1, a putative modulator of cystic fibrosis in the pig

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Structural and Inhibition Analysis Reveals the Mechanism of Selectivity of a Series of Aggrecanase Inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Murine mCLCA6 is an integral apical membrane protein of non-goblet cell enterocytes and co-localizes with the cystic fibrosis transmembrane conductance regulator

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Both cleavage products of the mCLCA3 protein are secreted soluble proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Blue native/SDS-PAGE analysis reveals reduced expression of the mClCA3 protein in cystic fibrosis knock-out mice.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

hCLCA1 and mCLCA3 are secreted non-integral membrane proteins and therefore are not ion channels

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Molecular characteristics and functional diversity of CLCA family members

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Inhibition of matrix metalloproteinase MMP-2 activates chloride current in human airway epithelial cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2 -activated Cl- channel proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Cloning and Characterization of Lung-Endothelial Cell Adhesion Molecule-1 Suggest It Is an Endothelial Chloride Channel

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Cloning of an epithelial chloride channel from bovine trachea

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Families of zinc metalloproteases.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887686

Membrane-anchored CD40 Is Processed by the Tumor Necrosis Factor-α-converting Enzyme

18 August 2018

1 reference

https://api.crossref.org/works/10.1007/S10059-011-0158-8

Association of the CLCA1 p.S357N variant with meconium ileus in European patients with cystic fibrosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22080371

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Furin directly cleaves proMMP-2 in the trans-Golgi network resulting in a nonfunctioning proteinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22080371

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

13 October 2017

1 reference

13 October 2017

1 reference