Rapid engineering of the geldanamycin biosynthesis pathway by Red/ET recombination and gene complementation (Q41819468)

12 October 2017

Rapid engineering of the geldanamycin biosynthesis pathway by Red/ET recombination and gene complementation (English)

1 reference

12 October 2017

Leandro Vetcher

1

1 reference

12 October 2017

Zong-Qiang Tian

2

1 reference

12 October 2017

Robert McDaniel

3

1 reference

12 October 2017

Andreas Rascher

4

1 reference

12 October 2017

W Peter Revill

5

1 reference

12 October 2017

C Richard Hutchinson

6

1 reference

12 October 2017

Zhihao Hu

7

1 reference

12 October 2017

language of work or name

English

0 references

publication date

1 April 2005

1 reference

Applied and Environmental Microbiology

12 October 2017

1 reference

12 October 2017

71

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12 October 2017

4

1 reference

12 October 2017

1829-1835

1 reference

Synthesis and biological activities of novel 17-aminogeldanamycin derivatives

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

An efficient method for creation and functional analysis of libraries of hybrid type I polyketide synthases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Novel biologically active natural and unnatural products

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

A novel erythromycin, 6-desmethyl erythromycin D, made by substituting an acyltransferase domain of the erythromycin polyketide synthase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Phage annealing proteins promote oligonucleotide-directed mutagenesis in Escherichia coli and mouse ES cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Geldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperones

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Point mutation of bacterial artificial chromosomes by ET recombination

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Novel macrolides through genetic engineering

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

A multiplasmid approach to preparing large libraries of polyketides

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Rapid modification of bacterial artificial chromosomes by ET-recombination.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

A new logic for DNA engineering using recombination in Escherichia coli

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Combinatorial biosynthesis of ‘unnatural’ natural products: the polyketide example

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Engineered biosynthesis of a complete macrolactone in a heterologous host

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Enzymatic Modification of Aminoglycoside Antibiotics: 3- N -Acetyltransferase with Broad Specificity that Determines Resistance to the Novel Aminoglycoside Apramycin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Geldanamycin, a new antibiotic

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1082551

Biosynthesis of the erythromycin macrolactone and a rational approach for producing hybrid macrolides

18 August 2018

1 reference

12 December 2020

erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

1 reference

12 December 2020

Recombinant polyketide synthesis in Streptomyces: engineering of improved host strains

1 reference

12 December 2020

Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains

1 reference

12 December 2020

A Novel Erythromycin, 6-Desmethyl Erythromycin D, Made by Substituting an Acyltransferase Domain of the Erythromycin Polyketide Synthase

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.56.543

10.1128/AEM.71.4.1829-1835.2005

12 April 2024

Identifiers

DOI

1 reference

release_rcmgk6474bbelftyc4nl3vdrdi

12 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rcmgk6474bbelftyc4nl3vdrdi

24 November 2022

mapped directly with Wikidata item

1 reference

12 October 2017

PubMed publication ID

15812008

1 reference