Hematopoietic stem cell development requires transient Wnt/β-catenin activity (Q41814485)

12 October 2017

Hematopoietic stem cell development requires transient Wnt/β-catenin activity (English)

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12 October 2017

5

Elaine Dzierzak

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12 October 2017

Cristina Ruiz-Herguido

1

1 reference

12 October 2017

Jordi Guiu

2

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12 October 2017

Teresa D'Altri

3

1 reference

12 October 2017

Julia Inglés-Esteve

4

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12 October 2017

Lluis Espinosa

6

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12 October 2017

Anna Bigas

7

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12 October 2017

language of work or name

English

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publication date

16 July 2012

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Journal of Experimental Medicine

12 October 2017

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12 October 2017

209

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12 October 2017

8

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12 October 2017

1457-1468

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describes a project that uses

12 October 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/3409499

inferred from PubMed Central ID database lookup

cites work

A somitic Wnt16/Notch pathway specifies haematopoietic stem cells

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Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

6 June 2018

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Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos

6 June 2018

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The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.

6 June 2018

1 reference

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Haploinsufficiency of Apc leads to ineffective hematopoiesis

6 June 2018

1 reference

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Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells

6 June 2018

1 reference

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Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

6 June 2018

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Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

6 June 2018

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6 June 2018

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Fate tracing reveals the endothelial origin of hematopoietic stem cells

6 June 2018

1 reference

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Contrasting responses of lymphoid progenitors to canonical and noncanonical Wnt signals

6 June 2018

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Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.

6 June 2018

1 reference

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Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment

6 June 2018

1 reference

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Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.

6 June 2018

1 reference

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Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood.

6 June 2018

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Of lineage and legacy: the development of mammalian hematopoietic stem cells

6 June 2018

1 reference

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Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo

6 June 2018

1 reference

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Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells

6 June 2018

1 reference

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Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Hematopoietic stem cell fate is established by the Notch-Runx pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Wnt signalling in stem cells and cancer

6 June 2018

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RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

6 June 2018

1 reference

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Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

6 June 2018

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The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility

6 June 2018

1 reference

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Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Wnt proteins are lipid-modified and can act as stem cell growth factors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

A role for Wnt signalling in self-renewal of haematopoietic stem cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Matrix2png: a utility for visualizing matrix data

6 June 2018

1 reference

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Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

6 June 2018

1 reference

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Identification and characterization of the familial adenomatous polyposis coli gene

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Beta-catenin does not regulate memory T cell phenotype

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409499

Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084/JEM.20120225

Definitive hematopoiesis is autonomously initiated by the AGM region

21 January 2018

1 reference

12 December 2020

An Unexpected Role for IL-3 in the Embryonic Development of Hematopoietic Stem Cells

1 reference

12 December 2020

Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis

1 reference

12 December 2020

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin

1 reference

12 December 2020

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20120225

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

22802352

1 reference