Targeted delivery of siRNA to cell death proteins in sepsis. (Q41768037)

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17 January 2020

title

Targeted delivery of siRNA to cell death proteins in sepsis (English)

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17 January 2020

5

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17 January 2020

Jonathan E. McDunn

12

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17 January 2020

13

Richard S Hotchkiss

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17 January 2020

11

Craig M Coopersmith

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17 January 2020

author name string

Pavan Brahmamdam

1

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17 January 2020

Eizo Watanabe

2

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17 January 2020

Jacqueline Unsinger

3

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17 January 2020

Katherine C Chang

4

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17 January 2020

Andrew S Hoekzema

6

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17 January 2020

Tony T Zhou

7

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17 January 2020

Jacquelyn S McDonough

8

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17 January 2020

Heather Holemon

9

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17 January 2020

Jeremy D Heidel

10

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17 January 2020

publication date

1 August 2009

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17 January 2020

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17 January 2020

volume

32

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17 January 2020

issue

2

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17 January 2020

page(s)

131-139

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19033888 AND SRC:MED&resulttype=core&format=json

Immunoparalysis and adverse outcomes from critical illness

17 January 2020

cites work

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Interfering with disease: a progress report on siRNA-based therapeutics

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6 June 2018

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Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.

6 June 2018

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Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference

6 June 2018

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Life in the balance: how BH3-only proteins induce apoptosis.

6 June 2018

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In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice

6 June 2018

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Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

6 June 2018

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The role of BH3-only proteins in the immune system

6 June 2018

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6 June 2018

Death receptor signaling

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Death receptor-induced cell killing

6 June 2018

1 reference

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

6 June 2018

1 reference

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

6 June 2018

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The pathophysiology and treatment of sepsis

6 June 2018

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Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

6 June 2018

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Cross-talk in cell death signaling

6 June 2018

1 reference

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

6 June 2018

1 reference

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Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis

6 June 2018

1 reference

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The effects of injury on the adaptive immune response

6 June 2018

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Neuroprotection by a caspase inhibitor in acute bacterial meningitis

6 June 2018

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Sepsis and septic shock--a review of laboratory models and a proposal

6 June 2018

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Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma

6 June 2018

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6 June 2018

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Optimization of gene expression in nonactivated circulating lymphocytes

18 August 2018

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Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity

18 August 2018

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Specific transgene expression in human and mouse CD4 cells using lentiviral vectors with regulatory sequences from the CD4 gene

18 August 2018

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Inhibition of Fas signaling prevents hepatic injury and improves organ blood flow during sepsis.

18 August 2018

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Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

18 August 2018

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Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis

3 November 2018

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12 December 2020

Depletion of dendritic cells, but not macrophages, in patients with sepsis

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12 December 2020

Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome

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12 December 2020

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

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12 December 2020

Spleen depletion in neonatal sepsis and chorioamnionitis

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12 December 2020

Anti-inflammatory therapies to treat sepsis and septic shock

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12 December 2020

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

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12 December 2020

Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure

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12 December 2020

Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways

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12 December 2020

Cecal ligation and puncture

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12 December 2020

Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis

1 reference

12 December 2020

10.1097/SHK.0B013E318194BCEE

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19033888 AND SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19033888 AND SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19033888

1 reference