SMADs: mediators and regulators of TGF-beta signaling (Q41732765)

8 October 2017

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title

SMADs: mediators and regulators of TGF-beta signaling (English)

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8 October 2017

Kretzschmar M

1

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8 October 2017

Massagué J

series ordinal

2

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8 October 2017

publication date

1 February 1998

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Current Opinion in Genetics & Development

8 October 2017

published in

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8 October 2017

volume

8

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8 October 2017

issue

1

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8 October 2017

page(s)

103-111

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Bone morphogenetic proteins: multifunctional regulators of vertebrate development

8 October 2017

cites work

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

TGFbeta signaling: receptors, transducers, and Mad proteins.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Cloning and characterization of a novel member of the human Mad gene family (MADH6)

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

TGF-beta signalling through the Smad pathway

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

1 reference

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7 January 2021

Smad4 and FAST-1 in the assembly of activin-responsive factor

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7 January 2021

A structural basis for mutational inactivation of the tumour suppressor Smad4

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo.

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Mechanism of TGFβ receptor inhibition by FKBP12

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Vascular MAD s: Two novel MAD -related genes selectively inducible by flow in human vascular endothelium

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Smad6 inhibits signalling by the TGF-β superfamily

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Daughters against dpp modulates dpp organizing activity in Drosophila wing development

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

FGF-4 and BMP-2 have opposite effects on limb growth.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Effect of protein and steroidal osteotropic agents on differentiation and epidermal growth factor-mediated growth of the CFK1 osseous cell line

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Mad-related genes in the human

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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https://api.crossref.org/works/10.1016/S0959-437X(98)80069-5

7 January 2021

10.1016/S0959-437X(98)80069-5

Identifiers

DOI

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8 October 2017

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