Histamine regulation of microglia: Gene-environment interaction in the regulation of central nervous system inflammation (Q41635706)

5 October 2017

Histamine regulation of microglia: Gene-environment interaction in the regulation of central nervous system inflammation (English)

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5 October 2017

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Christopher Pittenger

object named as

Christopher Pittenger

5

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author name string

Luciana Frick

1

1 reference

5 October 2017

Maximiliano Rapanelli

2

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5 October 2017

Eeman Abbasi

3

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5 October 2017

Hiroshi Ohtsu

4

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5 October 2017

2 July 2016

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Brain, Behavior, and Immunity

5 October 2017

1 reference

5 October 2017

57

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5 October 2017

326-337

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describes a project that uses

5 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5012904/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome

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Transcriptome Analysis of the Human Striatum in Tourette Syndrome

6 October 2017

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6 October 2017

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Mast cell secretory granules: armed for battle

6 October 2017

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Histamine: a new immunomodulatory player in the neuron-glia crosstalk

6 October 2017

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Inflammation in children and adolescents with neuropsychiatric disorders: a systematic review

6 October 2017

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Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior.

6 October 2017

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Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice

6 October 2017

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6 October 2017

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Microglia: an active player in the regulation of synaptic activity

6 October 2017

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Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

6 October 2017

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The histaminergic network in the brain: basic organization and role in disease

6 October 2017

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Repeated cortico-striatal stimulation generates persistent OCD-like behavior

6 October 2017

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6 October 2017

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Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice

6 October 2017

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The neglected role of histamine in Alzheimer's disease.

6 October 2017

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Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males

6 October 2017

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Immune-mediated animal models of Tourette syndrome

6 October 2017

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GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness

6 October 2017

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The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS

6 October 2017

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Histamine modulates microglia function

6 October 2017

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Histamine and neuroinflammation: insights from murine experimental autoimmune encephalomyelitis

6 October 2017

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Altered monocyte activation markers in Tourette's syndrome: a case-control study

6 October 2017

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Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

6 October 2017

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Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism

6 October 2017

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Wheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged mice

6 October 2017

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

6 October 2017

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Recent advances in Tourette syndrome

6 October 2017

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Microglia phenotype diversity.

6 October 2017

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Tourette syndrome (TS) bears a higher rate of inflammatory complications at the implanted hardware in deep brain stimulation (DBS).

6 October 2017

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Neurobiological substrates of Tourette's disorder

6 October 2017

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Hematopoietic origin of pathological grooming in Hoxb8 mutant mice

6 October 2017

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L-histidine decarboxylase and Tourette's syndrome

6 October 2017

1 reference

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Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice

6 October 2017

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Children with Tourette's syndrome may suffer immunoglobulin A dysgammaglobulinemia: preliminary report

6 October 2017

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The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS

6 October 2017

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T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.

6 October 2017

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Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

6 October 2017

1 reference

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Histamine in the nervous system

6 October 2017

1 reference

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Neuronal 'On' and 'Off' signals control microglia

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective.

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette's syndrome

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Mice lacking histidine decarboxylase exhibit abnormal mast cells

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Distribution of histamine H3-receptor binding in the normal human basal ganglia: comparison with Huntington's and Parkinson's disease cases

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

High levels of histidine decarboxylase in the striatum of mice and rats

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Decreased numbers of regulatory T cells suggest impaired immune tolerance in children with tourette syndrome: a preliminary study

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Histamine H3 receptor in primary mouse microglia inhibits chemotaxis, phagocytosis, and cytokine secretion.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Evaluation of basal ganglia and thalamic inflammation in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection and tourette syndrome: a positron emission tomographic (PET) study using 11C-[R]-PK11195.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Increase of histaminergic tuberomammillary neurons in narcolepsy

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Support of the histaminergic hypothesis in Tourette syndrome: association of the histamine decarboxylase gene in a large sample of families

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Greatly increased numbers of histamine cells in human narcolepsy with cataplexy

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Layer V cortical neurons require microglial support for survival during postnatal development.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Alterations in the histaminergic system in Alzheimer's disease: a postmortem study

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Functional increase of brain histaminergic signaling in Huntington's disease

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Localization of histamine H4 receptors in the central nervous system of human and rat.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Microarray analysis in Tourette syndrome postmortem putamen

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5012904

Histamine induces upregulated expression of histamine receptors and increases release of inflammatory mediators from microglia

19 August 2018

1 reference

12 December 2020

The subpopulation of microglia sensitive to neurotransmitters/neurohormones is modulated by stimulation with LPS, interferon-γ, and IL-4

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12 December 2020

Microglia-mediated IGF-I neuroprotection in the rd10 mouse model of retinitis pigmentosa

1 reference

12 December 2020

Impaired activation of the innate immune response to bacterial challenge in Tourette syndrome

1 reference

12 December 2020

10.1016/J.BBI.2016.07.002

Identifiers

DOI

1 reference

5 October 2017

1 reference

5 October 2017

PubMed publication ID

27381299

1 reference