PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis. (Q41619499)

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24 February 2020

title

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis (English)

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Clifton E Barry

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Veronique Dartois

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Laura E Via

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author name string

M Teresa Coleman

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Myungsun Lee

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Philana Ling Lin

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Lori E Dodd

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Pauline Maiello

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Youngran Kim

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Gwendolyn Marriner

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Charles Scanga

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Christopher Janssen

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Jing Wang

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Edwin Klein

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Sang Nae Cho

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JoAnne L Flynn

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language of work or name

English

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publication date

1 December 2014

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Science Translational Medicine

24 February 2020

published in

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volume

6

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issue

265

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page(s)

265ra167

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AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on activity in vitro

24 February 2020

cites work

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12 December 2020

Early events in Mycobacterium tuberculosis infection in cynomolgus macaques

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12 December 2020

Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates

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12 December 2020

Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

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12 December 2020

Population pharmacokinetics of linezolid in adults with pulmonary tuberculosis.

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12 December 2020

Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model

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12 December 2020

Experimental models of tuberculosis: can we trust the mouse?

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12 December 2020

Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

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12 December 2020

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

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12 December 2020

Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis

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12 December 2020

Adverse effects of antimicrobials via predictable or idiosyncratic inhibition of host mitochondrial components

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12 December 2020

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

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12 December 2020

Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

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12 December 2020

Linezolid for treatment of chronic extensively drug-resistant tuberculosis

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12 December 2020

Contradictory results with high-dosage rifamycin in mice and humans

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12 December 2020

Potential role of tedizolid phosphate in the treatment of acute bacterial skin infections

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12 December 2020

Can intermittent dosing optimize prolonged linezolid treatment of difficult multidrug-resistant tuberculosis?

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12 December 2020

Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus)

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12 December 2020

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

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12 December 2020

Linezolid to treat extensively drug-resistant TB: retrospective data are confirmed by experimental evidence

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12 December 2020

What we are watching--five top global infectious disease threats, 2012: a perspective from CDC's Global Disease Detection Operations Center

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12 December 2020

A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis

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12 December 2020

Pipeline of drugs for related diseases: tuberculosis

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12 December 2020

Bactericidal activity and mechanism of action of AZD5847, a novel oxazolidinone for treatment of tuberculosis

1 reference

12 December 2020

WHO's 2013 global report on tuberculosis: successes, threats, and opportunities

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12 December 2020

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

1 reference

12 December 2020

Outcomes of MDR/XDR-TB patients treated with linezolid: experience in Thailand

1 reference

12 December 2020

Assessment of linezolid efficacy, safety and tolerability in the treatment of tuberculosis: A retrospective case review

1 reference

12 December 2020

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis.

1 reference

12 December 2020

10.1126/SCITRANSLMED.3009500

Identifiers

DOI

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24 February 2020

PubMed publication ID

25473035

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