Mechanical impact induces cartilage degradation via mitogen activated protein kinases. (Q41578159)

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13 February 2020

title

Mechanical impact induces cartilage degradation via mitogen activated protein kinases (English)

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6

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James Martin

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author name string

L Ding

1

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E Heying

2

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N Nicholson

3

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N J Stroud

4

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G A Homandberg

5

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D Guo

7

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publication date

9 September 2010

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Osteoarthritis and Cartilage

13 February 2020

published in

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volume

18

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issue

11

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page(s)

1509-1517

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Analysing the role of endogenous matrix molecules in the development of osteoarthritis.

13 February 2020

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6 June 2018

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Induction of Chondrocyte Apoptosis Following Impact Load

6 June 2018

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Molecular pathology and pathobiology of osteoarthritic cartilage

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Chondrocyte necrosis and apoptosis in impact damaged articular cartilage

6 June 2018

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Synovial joint degeneration and the syndrome of osteoarthritis

6 June 2018

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The reactions of articular cartilage to experimental wounding: role of apoptosis

6 June 2018

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Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis.

6 June 2018

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Chondrocyte-derived apoptotic bodies and calcification of articular cartilage

6 June 2018

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The association of knee injury and obesity with unilateral and bilateral osteoarthritis of the knee

6 June 2018

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Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants.

6 June 2018

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6 June 2018

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Telopeptides of type II collagen upregulate proteinases and damage cartilage but are less effective than highly active fibronectin fragments

6 June 2018

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Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression

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Cathepsins B, K, and L are regulated by a defined collagen type II peptide via activation of classical protein kinase C and p38 MAP kinase in articular chondrocytes

19 August 2018

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19 August 2018

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TNFα suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF‐κB signaling pathways

19 August 2018

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12 December 2020

Survival of articular cartilage after controlled impact

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12 December 2020

Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants

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12 December 2020

Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology

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12 December 2020

Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants

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12 December 2020

AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis

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12 December 2020

Effect of impact load on articular cartilage: cell metabolism and viability, and matrix water content

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12 December 2020

Viability and apoptosis of human chondrocytes in osteochondral fragments following joint trauma

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12 December 2020

The cartilage chondrolytic mechanism of fibronectin fragments involves MAP kinases: comparison of three fragments and native fibronectin

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12 December 2020

ROS-mediated p38alpha MAPK activation and ERK inactivation responsible for upregulation of Fas and FasL and autocrine Fas-mediated cell death in Taiwan cobra phospholipase A(2)-treated U937 cells

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12 December 2020

Cellular responses of embryonic hyaline cartilage to experimental wounding in vitro

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12 December 2020

10.1016/J.JOCA.2010.08.014

Identifiers

DOI

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13 February 2020

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13 February 2020

PubMed publication ID

20813194

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