Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. (Q41575018)

4 October 2017

Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. (English)

1 reference

4 October 2017

1 reference

Tom Zhao

1

1 reference

4 October 2017

Jiangyuan Gao

2

1 reference

4 October 2017

Jenifer Van

3

1 reference

4 October 2017

Eleanor To

4

1 reference

4 October 2017

Aikun Wang

5

1 reference

4 October 2017

Sijia Cao

6

1 reference

4 October 2017

Jing Z Cui

7

1 reference

4 October 2017

Jian-Ping Guo

8

1 reference

4 October 2017

Moonhee Lee

9

1 reference

4 October 2017

Patrick L McGeer

10

1 reference

4 October 2017

Joanne A Matsubara

11

1 reference

4 October 2017

24 June 2015

1 reference

Journal of Neuroinflammation

4 October 2017

1 reference

4 October 2017

12

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4 October 2017

121

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Creative Commons Attribution 4.0 International

4 October 2017

start time

24 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells

6 June 2018

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What does complement do in Alzheimer's disease? Old molecules with new insights

6 June 2018

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Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration.

6 June 2018

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Altered cytokine profiles of human retinal pigment epithelium: oxidant injury and replicative senescence

6 June 2018

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Balance between autophagic pathways preserves retinal homeostasis

6 June 2018

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Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration

6 June 2018

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DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88

6 June 2018

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The diverse and complex roles of NF-κB subunits in cancer

6 June 2018

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Elevated membrane attack complex in human choroid with high risk complement factor H genotypes

6 June 2018

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Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration.

6 June 2018

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Viewing Ageing Eyes: Diverse Sites of Amyloid Beta Accumulation in the Ageing Mouse Retina and the Up-Regulation of Macrophages

6 June 2018

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Complement: a key system for immune surveillance and homeostasis

6 June 2018

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Differential accumulation of secreted AbetaPP metabolites in ocular fluids

6 June 2018

1 reference

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The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited

6 June 2018

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Soluble and mature amyloid fibrils in drusen deposits

6 June 2018

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Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells

6 June 2018

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Para-inflammation in the aging retina.

6 June 2018

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The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration

6 June 2018

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Complement-associated deposits in the human retina

6 June 2018

1 reference

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Complement factor B gene regulation: synergistic effects of TNF-alpha and IFN-gamma in macrophages

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration

6 June 2018

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Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

6 June 2018

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The role of the retinal pigment epithelium: topographical variation and ageing changes

6 June 2018

1 reference

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Complement component C3 production in IL-1beta-stimulated human intestinal epithelial cells is blocked by NF-kappaB inhibitors and by transfection with ser 32/36 mutant IkappaBalpha

6 June 2018

1 reference

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Specific binding of a hepatoma nuclear factor to the NF.kappa B/H2TF1 recognition motif found in the C4 promoter, but not in the Slp promoter.

6 June 2018

1 reference

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Complement activation by beta-amyloid in Alzheimer disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Amyloid beta-peptide is produced by cultured cells during normal metabolism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

The complement membrane attack complex triggers intracellular Ca2 fluxes leading to NLRP3 inflammasome activation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Transformation of amyloid β(1-40) oligomers into fibrils is characterized by a major change in secondary structure

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Immune activation in retinal aging: a gene expression study

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Soluble Amyloid Aβ-(1–40) Exists as a Stable Dimer at Low Concentrations

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Aspartate residue 7 in amyloid beta-protein is critical for classical complement pathway activation: implications for Alzheimer's disease pathogenesis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486438

Complement haemolytic activity (classical and alternative pathways), C3, C4 and factor B titres in healthy children

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26104676

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26104676

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12974-015-0337-1

1 reference

Dimensions Publication ID

4 October 2017

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12974-015-0337-1

1 reference

4 October 2017

PubMed publication ID

26104676

1 reference