Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration (Q41548418)

3 October 2017

Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration (English)

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3 October 2017

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1

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11 June 2020

Enrico Grisan

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11 June 2020

Alessandro Mongera

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11 June 2020

Natascia Tiso

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11 June 2020

author name string

Estefania Tarifeño-Saldivia

2

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11 June 2020

Marco Schiavone

4

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11 June 2020

Margherita Peron

5

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11 June 2020

Olivier Ek

7

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11 June 2020

Nicole Schmitner

8

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11 June 2020

Dirk Meyer

9

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11 June 2020

Bernard Peers

10

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11 June 2020

Francesco Argenton

12

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11 June 2020

language of work or name

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publication date

29 August 2017

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3 October 2017

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11 June 2020

volume

7

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11 June 2020

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1

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11 June 2020

page(s)

9605

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Creative Commons Attribution 4.0 International

11 June 2020

copyright license

start time

29 August 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

DESeq2

object named as

DESeq

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes

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ptf1a , ela3l- cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae

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The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis.

6 June 2018

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Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

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TCF7L2 and glucose metabolism: time to look beyond the pancreas

6 June 2018

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Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

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Vascular development in the zebrafish

6 June 2018

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Angiopoietin 2 alters pancreatic vascularization in diabetic conditions

6 June 2018

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Exocrine Pancreatic Insufficiency in Diabetes Mellitus: A Complication of Diabetic Neuropathy or a Different Type of Diabetes?

6 June 2018

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DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish.

6 June 2018

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Differential expression analysis for sequence count data

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The Role of Wnt Signaling in Physiological and Pathological Angiogenesis

6 June 2018

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Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes

6 June 2018

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Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

6 June 2018

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Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas

6 June 2018

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Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis

6 June 2018

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'Giving and taking': endothelial and beta-cells in the islets of Langerhans

6 June 2018

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Wnt signaling in pancreatic islets

6 June 2018

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The role of blood vessels, endothelial cells, and vascular pericytes in insulin secretion and peripheral insulin action

6 June 2018

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Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice

6 June 2018

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Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling

6 June 2018

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Zebrafish pancreas development.

6 June 2018

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Interactions between the endocrine and exocrine pancreas and their clinical relevance.

6 June 2018

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Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

6 June 2018

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The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus

6 June 2018

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RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

6 June 2018

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T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine

6 June 2018

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Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

6 June 2018

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Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

6 June 2018

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Wnt signaling regulates pancreatic beta cell proliferation

6 June 2018

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Subvoxel precise skeletons of volumetric data based on fast marching methods

6 June 2018

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Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase

6 June 2018

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Distinct delta and jagged genes control sequential segregation of pancreatic cell types from precursor pools in zebrafish.

6 June 2018

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TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

6 June 2018

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

6 June 2018

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Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina.

6 June 2018

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Beta-catenin is essential for pancreatic acinar but not islet development

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

A possible role for the canonical Wnt pathway in endocrine cell development in chicks

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Formation of the digestive system in zebrafish. II. Pancreas morphogenesis.

6 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

In vivo imaging of embryonic vascular development using transgenic zebrafish

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Stages of embryonic development of the zebrafish

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Monitoring Wnt Signaling in Zebrafish Using Fluorescent Biosensors.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling.

19 August 2018

1 reference

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VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation.

19 August 2018

1 reference

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Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Analysis of beta cell proliferation dynamics in zebrafish.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Generation of living color transgenic zebrafish to trace somatostatin-expressing cells and endocrine pancreas organization.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Multi-stencils fast marching methods: a highly accurate solution to the eikonal equation on cartesian domains

19 August 2018

1 reference

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Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Stabilization of beta-catenin impacts pancreas growth.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Role of VEGF-A in vascularization of pancreatic islets

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Early appearance of pancreatic hormone-expressing cells in the zebrafish embryo

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5575064

Multiple Comparisons among Means

19 August 2018

1 reference

https://api.crossref.org/works/10.1038/S41598-017-09867-X

TCF7L2 and Diabetes: A Tale of Two Tissues, and of Two Species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/S41598-017-09867-X

7 January 2021

Induction of hyperglycaemia in zebrafish (Danio rerio) leads to morphological changes in the retina

1 reference

https://api.crossref.org/works/10.1038/S41598-017-09867-X

7 January 2021

Roles for Fgf signaling during zebrafish fin regeneration

1 reference

https://api.crossref.org/works/10.1038/S41598-017-09867-X

7 January 2021

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1 reference

https://api.crossref.org/works/10.1038/S41598-017-09867-X

7 January 2021

10.1038/S41598-017-09867-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28851992 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28851992 AND SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

28851992

1 reference