Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice (Q41525208)

2 October 2017

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice (English)

1 reference

2 October 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Christina L Papke

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Jungsil Kim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Lea-Jeanne Ringuette

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Qing-Jun Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Zhi-Ping Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Hamid Mirzaei

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Jessica E Wagenseil

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Elaine C Davis

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

Hiromi Yanagisawa

10

1 reference

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5 June 2020

publication date

20 October 2015

1 reference

2 October 2017

1 reference

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5 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

issue

399

1 reference

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5 June 2020

page(s)

ra105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections

5 June 2020

cites work

1 reference

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Atenolol versus losartan in children and young adults with Marfan's syndrome

6 June 2018

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Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome.

6 June 2018

1 reference

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PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart

6 June 2018

1 reference

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Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma

6 June 2018

1 reference

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Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections

6 June 2018

1 reference

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Aortic remodeling after transverse aortic constriction in mice is attenuated with AT1 receptor blockade.

6 June 2018

1 reference

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Functions of cofilin in cell locomotion and invasion.

6 June 2018

1 reference

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Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice.

6 June 2018

1 reference

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Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Cloud CPFP: a shotgun proteomics data analysis pipeline using cloud and high performance computing

6 June 2018

1 reference

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Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Rare, Nonsynonymous Variant in the Smooth Muscle-Specific Isoform of Myosin Heavy Chain, MYH11 , R247C, Alters Force Generation in the Aorta and Phenotype of Smooth Muscle Cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formation

6 June 2018

1 reference

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Actin dynamics and turnover in cell motility.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Dynamic molecular processes mediate cellular mechanotransduction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Phosphorylation of Ser 402 impedes phosphatase activity of slingshot 1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

The importance of elastin to aortic development in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Transverse aortic constriction in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Altered TGFbeta signaling and cardiovascular manifestations in patients with autosomal recessive cutis laxa type I caused by fibulin-4 deficiency

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase

6 June 2018

1 reference

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Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like

6 June 2018

1 reference

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Phosphoinositide 3-kinase inhibitor (wortmannin) inhibits pancreatic cancer cell motility and migration induced by hyaluronan in vitro and peritoneal metastasis in vivo

6 June 2018

1 reference

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Reactive oxygen species regulate a slingshot-cofilin activation pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Molecular dissection of the mechanisms of substrate recognition and F-actin-mediated activation of cofilin-phosphatase Slingshot-1.

6 June 2018

1 reference

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Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction

6 June 2018

1 reference

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Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.

6 June 2018

1 reference

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Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

6 June 2018

1 reference

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Aneurysm syndromes caused by mutations in the TGF-beta receptor

6 June 2018

1 reference

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Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Stretch-inducible expression of the angiogenic factor CCN1 in vascular smooth muscle cells is mediated by Egr-1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis

6 June 2018

1 reference

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Proteins of the ADF/cofilin family: essential regulators of actin dynamics

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Phosphorylation of Ser-3 of cofilin regulates its essential function on actin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Signal transduction and actin filament organization

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Comparison of ANG II with other growth factors on Egr-1 and matrix gene expression in cardiac fibroblasts

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Mutations in the human gene for fibrillin-1 (FBN1) in the Marfan syndrome and related disorders

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Patients with Ehlers-Danlos syndrome type IV lack type III collagen

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

CPFP: a central proteomics facilities pipeline

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Characterization of the bovine angiotensin converting enzyme promoter: essential roles of Egr-1, ATF-2 and Ets-1 in the regulation by phorbol ester

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Compound heterozygous mutations in fibulin-4 causing neonatal lethal pulmonary artery occlusion, aortic aneurysm, arachnodactyly, and mild cutis laxa.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Postnatal development of blood pressure and baroreflex in mice

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5572214

Immunolocalization of microfibril and microfibril-associated proteins in the subendothelial matrix of the developing mouse aorta

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26486174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Smooth muscle cell to elastic lamina connections in developing mouse aorta. Role in aortic medial organization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26486174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26486174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.AAB3141

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

26486174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486174 AND SRC:MED&resulttype=core&format=json