The promise of epigenomic therapeutics in pancreatic cancer (Q41473804)

1 October 2017

1 reference

25 September 2020

The promise of epigenomic therapeutics in pancreatic cancer (English)

1 reference

pancreatic ductal carcinoma

1 October 2017

1 reference

25 September 2020

1 reference

25 September 2020

1 reference

25 September 2020

1 reference

PubMed publication ID

27337224

author name string

Gwen A Lomberk

series ordinal

1

1 reference

1 October 2017

Juan Iovanna

series ordinal

2

1 reference

1 October 2017

Raul Urrutia

series ordinal

3

1 reference

1 October 2017

language of work or name

1 reference

23 June 2016

1 reference

1 October 2017

1 June 2016

5 references

21 March 2019

24 March 2019

3 April 2019

8 September 2019

25 September 2020

6 references

1 October 2017

21 March 2019

24 March 2019

3 April 2019

8 September 2019

25 September 2020

8

1 reference

1 October 2017

6

1 reference

1 October 2017

831-842

1 reference

Creative Commons Attribution-NonCommercial-NoDerivatives

1 October 2017

5 references

21 March 2019

24 March 2019

3 April 2019

8 September 2019

25 September 2020

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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The Triple-Code Model for Pancreatic Cancer: Cross Talk Among Genetics, Epigenetics, and Nuclear Structure

11 June 2018

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Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents

11 June 2018

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Whole genomes redefine the mutational landscape of pancreatic cancer

11 June 2018

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KATs in cancer: functions and therapies

11 June 2018

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11 June 2018

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Therapeutic targeting of microRNAs: current status and future challenges

11 June 2018

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Targeting histone lysine demethylases - progress, challenges, and the future

11 June 2018

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DNA methyltransferases: a novel target for prevention and therapy

11 June 2018

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Targeting bromodomains: epigenetic readers of lysine acetylation

11 June 2018

1 reference

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Interpreting the language of histone and DNA modifications

11 June 2018

1 reference

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Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention

11 June 2018

1 reference

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Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

11 June 2018

1 reference

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Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis

11 June 2018

1 reference

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Histone deacetylases and cancer.

11 June 2018

1 reference

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Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells

11 June 2018

1 reference

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Epigenetic protein families: a new frontier for drug discovery

11 June 2018

1 reference

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Histone recognition and large-scale structural analysis of the human bromodomain family

11 June 2018

1 reference

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Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases

11 June 2018

1 reference

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Structural Chemistry of Human SET Domain Protein Methyltransferases

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Targeting Histone Demethylases: A New Avenue for the Fight against Cancer

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Readers of histone modifications

11 June 2018

1 reference

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Epigenetic Silencing of Tumor Suppressor Genes in Pancreatic Cancer

11 June 2018

1 reference

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Histone arginine methylation

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Genome-scale DNA methylation analysis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Global levels of histone modifications predict prognosis in different cancers

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

MicroRNAs: target recognition and regulatory functions

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2.

11 June 2018

1 reference

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A work in progress: the clinical development of histone deacetylase inhibitors

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Reactivation of epigenetically silenced genes by DNA methyltransferase inhibitors: basic concepts and clinical applications

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

An elaborate pathway required for Ras-mediated epigenetic silencing

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

DNA methyltransferases as targets for cancer therapy

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Precursor lesions of pancreatic cancer: molecular pathology and clinical implications

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Expression profiling identifies microRNA signature in pancreatic cancer

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

The diverse functions of histone lysine methylation

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Expression profiles of a human pancreatic cancer cell line upon induction of apoptosis search for modulators in cancer therapy

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

The history of cancer epigenetics

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Histone acetyltransferases: function, structure, and catalysis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Progression model for pancreatic cancer.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Histone acetylation and an epigenetic code

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

The language of covalent histone modifications

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

A genetic model for colorectal tumorigenesis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

BLUEPRINT to decode the epigenetic signature written in blood.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5066125

Hypermethylation of multiple genes in pancreatic adenocarcinoma

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27337224

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2217/EPI-2015-0016

1 reference

1 October 2017

1 reference

1 October 2017

PubMed publication ID

27337224

1 reference