Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance (Q41093923)

26 September 2017

Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance (English)

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26 September 2017

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13 June 2020

Jayanta Debnath

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13 June 2020

Shingo Kajimura

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13 June 2020

author name string

Svetlana Altshuler-Keylin

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13 June 2020

Yutaka Hasegawa

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13 June 2020

Kenji Ikeda

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13 June 2020

Haemin Hong

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13 June 2020

Qianqian Kang

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13 June 2020

Yangyu Yang

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13 June 2020

Rushika M Perera

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13 June 2020

publication date

24 August 2016

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26 September 2017

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13 June 2020

volume

24

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issue

3

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page(s)

402-419

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Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.

13 June 2020

cites work

1 reference

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A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis

26 September 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

26 September 2017

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Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

26 September 2017

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Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase

26 September 2017

1 reference

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Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure

26 September 2017

1 reference

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Brown and Beige Fat: Physiological Roles beyond Heat Generation

26 September 2017

1 reference

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Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism

26 September 2017

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Genetic and functional characterization of clonally derived adult human brown adipocytes

26 September 2017

1 reference

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Mitochondrial turnover: a phenotype distinguishing brown adipocytes from interscapular brown adipose tissue and white adipose tissue.

26 September 2017

1 reference

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Loss of Atg12, but not Atg5, in pro-opiomelanocortin neurons exacerbates diet-induced obesity

26 September 2017

1 reference

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Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.

26 September 2017

1 reference

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Cellular origins of cold-induced brown adipocytes in adult mice

26 September 2017

1 reference

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Nutrient-sensing nuclear receptors coordinate autophagy

26 September 2017

1 reference

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Transcriptional regulation of autophagy by an FXR-CREB axis

26 September 2017

1 reference

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Ebf2 is a selective marker of brown and beige adipogenic precursor cells

26 September 2017

1 reference

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Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity

26 September 2017

1 reference

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IRF4 is a key thermogenic transcriptional partner of PGC-1α

26 September 2017

1 reference

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Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans.

26 September 2017

1 reference

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Tracking adipogenesis during white adipose tissue development, expansion and regeneration

26 September 2017

1 reference

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Cold acclimation recruits human brown fat and increases nonshivering thermogenesis.

26 September 2017

1 reference

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Bi-directional interconversion of brite and white adipocytes

26 September 2017

1 reference

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ZKSCAN3 is a master transcriptional repressor of autophagy

26 September 2017

1 reference

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A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods

26 September 2017

1 reference

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Human BAT possesses molecular signatures that resemble beige/brite cells

26 September 2017

1 reference

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PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors.

26 September 2017

1 reference

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Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

26 September 2017

1 reference

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Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

26 September 2017

1 reference

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In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding

26 September 2017

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Autophagy: renovation of cells and tissues

26 September 2017

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Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling

26 September 2017

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TFEB links autophagy to lysosomal biogenesis

26 September 2017

1 reference

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Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat.

26 September 2017

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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

26 September 2017

1 reference

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

26 September 2017

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Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes

26 September 2017

1 reference

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Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

26 September 2017

1 reference

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Autophagy regulates adipose mass and differentiation in mice

26 September 2017

1 reference

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Regulation mechanisms and signaling pathways of autophagy

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

A gene network regulating lysosomal biogenesis and function

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Identification and importance of brown adipose tissue in adult humans

26 September 2017

1 reference

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Cold-activated brown adipose tissue in healthy men

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

PRDM16 controls a brown fat/skeletal muscle switch

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

26 September 2017

1 reference

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Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse

26 September 2017

1 reference

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In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Recruited brown adipose tissue as an antiobesity agent in humans

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

14 June 2018

1 reference

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PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Orexin restores aging-related brown adipose tissue dysfunction in male mice.

14 June 2018

1 reference

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Evidence for two types of brown adipose tissue in humans.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Defective regulation of adipose tissue autophagy in obesity.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Utilizing flow cytometry to monitor autophagy in living mammalian cells

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023491

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27568548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Altered autophagy in human adipose tissues in obesity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27568548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Autophagy activity is up-regulated in adipose tissue of obese individuals and modulates proinflammatory cytokine expression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27568548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2016.08.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27568548 AND SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27568548 AND SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

27568548

1 reference