Contribution of programmed cell death receptor (PD)-1 to Kupffer cell dysfunction in murine polymicrobial sepsis (Q40989836)

25 September 2017

Contribution of programmed cell death receptor (PD)-1 to Kupffer cell dysfunction in murine polymicrobial sepsis (English)

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25 September 2017

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6

Alfred Ayala

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25 September 2017

Fei Wang

1

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25 September 2017

Xin Huang

2

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25 September 2017

Chun-Shiang Chung

3

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25 September 2017

Yaping Chen

4

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25 September 2017

Noelle A Hutchins

5

1 reference

25 September 2017

10 June 2016

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American Journal of Physiology - Gastrointestinal and Liver Physiology

25 September 2017

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25 September 2017

311

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25 September 2017

2

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25 September 2017

G237-45

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describes a project that uses

25 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5007287/fullTextXML

inferred from PubMed Central ID database lookup

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The new normal: immunomodulatory agents against sepsis immune suppression

25 September 2017

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Sepsis-induced potentiation of peritoneal macrophage migration is mitigated by programmed cell death receptor-1 gene deficiency.

25 September 2017

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Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1.

25 September 2017

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25 September 2017

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Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients.

25 September 2017

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Deficiency of Bid protein reduces sepsis-induced apoptosis and inflammation, while improving septic survival

25 September 2017

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PD-1 signaling in primary T cells

25 September 2017

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PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

25 September 2017

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The liver as a lymphoid organ

25 September 2017

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The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock

25 September 2017

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The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients

25 September 2017

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B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells

25 September 2017

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Polymicrobial sepsis enhances clearance of apoptotic immune cells by splenic macrophages

25 September 2017

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Apoptosis and caspases regulate death and inflammation in sepsis

25 September 2017

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Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways

25 September 2017

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Activation of common antiviral pathways can potentiate inflammatory responses to septic shock

25 September 2017

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Novel therapies for sepsis: a review

25 September 2017

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Leukocyte apoptosis and its significance in sepsis and shock

25 September 2017

1 reference

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Sepsis-induced changes in macrophage co-stimulatory molecule expression: CD86 as a regulator of anti-inflammatory IL-10 response

25 September 2017

1 reference

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Therapeutic intervention and targets for sepsis

25 September 2017

1 reference

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Sepsis-induced SOCS-3 expression is immunologically restricted to phagocytes

25 September 2017

1 reference

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Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis

25 September 2017

1 reference

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Monocyte CD40 expression in severe sepsis

25 September 2017

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STAT4 is required for antibacterial defense but enhances mortality during polymicrobial sepsis

25 September 2017

1 reference

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Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

25 September 2017

1 reference

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Apoptosis in sepsis: a new target for therapeutic exploration

25 September 2017

1 reference

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Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis

25 September 2017

1 reference

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Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis

25 September 2017

1 reference

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Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007287

Kupffer cells protect liver sinusoidal endothelial cells from Fas-dependent apoptosis in sepsis by down-regulating gp130.

25 September 2017

1 reference

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Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release

15 June 2018

1 reference

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Immediate burn wound excision restores antibody synthesis to bacterial antigen

15 June 2018

1 reference

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Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80

15 June 2018

1 reference

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Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNF) release

15 June 2018

1 reference

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Effect of IL-10 antisense gene therapy in severely burned mice intradermally infected with MRSA.

15 June 2018

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Enhanced regulatory T cell activity is an element of the host response to injury.

19 August 2018

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Antigen presenting cells (APCs) from thermally injured and/or septic rats modulate CD4 T cell responses of naive rat.

19 August 2018

1 reference

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Akt decreases lymphocyte apoptosis and improves survival in sepsis

19 August 2018

1 reference

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Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007287

Mechanism of immune dysfunction in sepsis: inducible nitric oxide-meditated alterations in p38 MAPK activation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007287

GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007287

Role of Kupffer cells in interleukin-6 release following trauma-hemorrhage and resuscitation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007287

Neither Fas Ligand nor Endotoxin Is Responsible for Inducible Peritoneal Phagocyte Apoptosis during Sepsis/Peritonitis

19 August 2018

1 reference

12 December 2020

Early But Not Late Burn Wound Excision Partially Restores Viral-Specific T Lymphocyte Cytotoxicity

1 reference

12 December 2020

What is the role of interleukin 10 in polymicrobial sepsis: anti-inflammatory agent or immunosuppressant?

1 reference

12 December 2020

Compensatory anti-inflammatory response syndrome

1 reference

12 December 2020

Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis

1 reference

12 December 2020

Mechanism of Splenic Immunosuppression During Sepsis

1 reference

12 December 2020

Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor)

1 reference

12 December 2020

Injury-induced suppression of effector T cell immunity requires CD1d-positive APCs and CD1d-restricted NKT cells

1 reference

12 December 2020

Monocyte deactivation in septic patients: restoration by IFN-gamma treatment

1 reference

12 December 2020

Septic mucosal intraepithelial lymphoid immune suppression: role for nitric oxide not interleukin-10 or transforming growth factor-beta

1 reference

12 December 2020

Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock

1 reference

12 December 2020

Major Injury Induces Increased Production of Interleukin-10 by Cells of the Immune System With a Negative Impact on Resistance to Infection

1 reference

12 December 2020

Sepsis induces an early increased spontaneous release of hepatocellular stimulatory factor (interleukin-6) by Kupffer cells in both endotoxin tolerant and intolerant mice

1 reference

12 December 2020

Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin

1 reference

12 December 2020

SOCS-1 is a central mediator of steroid-increased thymocyte apoptosis and decreased survival following sepsis

1 reference

12 December 2020

Role of M2b macrophages in the acceleration of bacterial translocation and subsequent sepsis in mice exposed to whole body [137Cs] γ-irradiation

1 reference

12 December 2020

M2b Monocytes Predominated in Peripheral Blood of Severely Burned Patients

1 reference

12 December 2020

Identifiers

DOI

10.1152/AJPGI.00371.2015

1 reference

25 September 2017

1 reference

25 September 2017

PubMed publication ID

27288425

1 reference