A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells. (Q40896676)

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4 November 2019

title

A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells (English)

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4 November 2019

1

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4 November 2019

author name string

M Pearce

2

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4 November 2019

L S Steelman

3

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4 November 2019

R A Franklin

4

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4 November 2019

S A McCarthy

5

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4 November 2019

H Cherwinski

6

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4 November 2019

M McMahon

7

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4 November 2019

J A McCubrey

8

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4 November 2019

language of work or name

English

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publication date

1 January 2000

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4 November 2019

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4 November 2019

volume

19

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4 November 2019

issue

4

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4 November 2019

page(s)

526-536

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Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase

4 November 2019

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Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells

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Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells

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A Role for the MEK/MAPK Pathway in PMA-Induced Cell Cycle Arrest: Modulation of Megakaryocytic Differentiation of K562 Cells

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Biochemical and biological analysis of Mek1 phosphorylation site mutants

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Signaling through the hematopoietic cytokine receptors.

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Bcl-2 phosphorylation required for anti-apoptosis function

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Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

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Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.

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Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors

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Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

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Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.

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Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

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Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

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The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells

21 January 2018

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Characterization of proteins binding the 3' regulatory region of the IL-3 gene in IL-3-dependent and autocrine-transformed hematopoietic cells.

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7 January 2021

Transformation of mammalian cells by constitutively active MAP kinase kinase

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7 January 2021

Cytokine receptors and signal transduction

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7 January 2021

The role of serine/threonine phosphorylation in hematopoietic cytokine receptor signal transduction

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203337

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698522 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 November 2019

1037872122

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1 reference