Peptidomimetic design (Q40843326)

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Language	Label	Description	Also known as
English	Peptidomimetic design	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

1 reference

Europe PubMed Central

Peptidomimetic design (English)

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Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Ripka AS

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Rich DH

2

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Europe PubMed Central

PubMed publication ID

24 September 2017

publication date

1 August 1998

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Current Opinion in Chemical Biology

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Europe PubMed Central

PubMed publication ID

24 September 2017

2

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Europe PubMed Central

PubMed publication ID

24 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

441-452

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Europe PubMed Central

PubMed publication ID

24 September 2017

Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design

1 reference

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The "One-Bead-One-Compound" Combinatorial Library Method

1 reference

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Modern computational chemistry and drug discovery: structure generating programs

1 reference

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Potent new inhibitors of human renin

1 reference

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Peptidomimetics derived from natural products

1 reference

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Locating ligand-binding sites in 7TM receptors by protein engineering.

1 reference

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Design of potent and selective human cathepsin K inhibitors that span the active site

1 reference

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Crystal structure of human cathepsin K complexed with a potent inhibitor

1 reference

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Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor

1 reference

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First examples of peptidomimetic inhibitors of interleukin-1 beta converting enzyme

1 reference

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Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors

1 reference

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Ureido-based peptidomimetic inhibitor of herpes simplex virus ribonucleotide reductase: an investigation of inhibitor bioactive conformation.

1 reference

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Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase with improved in vivo antiviral activity

1 reference

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Design, synthesis, and in vitro activities of benzamide-core glycoprotein IIb/IIIa antagonists: 2,3-diaminopropionic acid derivatives as surrogates of aspartic acid

1 reference

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Non-peptide RGD surrogates which mimic a Gly-Asp beta-turn: potent antagonists of platelet glycoprotein IIb-IIIa

1 reference

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From peptide to non-peptide. 3. Atropisomeric GPIIbIIIa antagonists containing the 3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione nucleus

1 reference

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Nonpeptide glycoprotein IIb/IIIa inhibitors: substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists

1 reference

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Rational Design and Synthesis of Novel, Potent Bis-phenylamidine Carboxylate Factor Xa Inhibitors

1 reference

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Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors

1 reference

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based on heuristic

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X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

1 reference

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based on heuristic

inferred from DOI database lookup

Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor Xa

1 reference

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based on heuristic

inferred from DOI database lookup

Discovery and development of the novel potent orally active thrombin inhibitor N-(9-hydroxy-9-fluorenecarboxy)prolyl trans-4-aminocyclohexylmethyl amide (L-372,460): coapplication of structure-based design and rapid multiple analogue synthesis on so

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Design of highly potent noncovalent thrombin inhibitors that utilize a novel lipophilic binding pocket in the thrombin active site

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(98)80119-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of human α‐thrombin complexed with LY178550, a nonpeptidyl, active site‐directed inhibitor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Amidino-substituted aromatic heterocycles as probes of the specificity pocket of trypsin-like proteases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(98)80119-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Design and synthesis of potent and highly selective thrombin inhibitors

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(98)80119-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes

1 reference

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based on heuristic

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Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

1 reference

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based on heuristic

inferred from DOI database lookup

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

1 reference

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based on heuristic

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Ras Farnesyltransferase: A New Therapeutic Target

1 reference

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based on heuristic

inferred from DOI database lookup

Farnesyltransferase as a target for anticancer drug design

1 reference

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based on heuristic

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Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.

1 reference

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Discovery of novel nonpeptide tricyclic inhibitors of Ras farnesyl protein transferase

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Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

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Matrix Metalloproteinase Inhibitors in Arthritis

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Identifiers

10.1016/S1367-5931(98)80119-1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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