Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway (Q40817321)

24 September 2017

title

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway (English)

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24 September 2017

D Koul

1

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24 September 2017

Y Yao

2

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24 September 2017

J L Abbruzzese

3

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24 September 2017

W K Yung

4

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24 September 2017

S A Reddy

5

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24 September 2017

language of work or name

English

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publication date

12 January 2001

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

276

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24 September 2017

issue

14

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24 September 2017

page(s)

11402-11408

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The NF-kappa B and I kappa B proteins: new discoveries and insights

24 September 2017

cites work

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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IKAP is a scaffold protein of the IkappaB kinase complex

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21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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21 January 2018

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21 January 2018

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

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Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation

21 January 2018

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

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21 January 2018

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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

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Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways

21 January 2018

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NF-kappa B/Rel family members are physically associated phosphoproteins

21 January 2018

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21 January 2018

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Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

21 January 2018

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

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Phosphatidylinositol 3-kinase is recruited to a specific site in the activated IL-1 receptor I

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M007806200

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24 September 2017

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