Impact of SDS surfactant on the interactions of Cu(2 ) ions with the amyloidogenic region of human prion protein. (Q40801758)

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18 February 2020

title

Impact of SDS surfactant on the interactions of Cu(2 ) ions with the amyloidogenic region of human prion protein (English)

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author name string

Aleksandra Hecel

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Caterina Migliorini

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Daniela Valensin

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Marek Luczkowski

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language of work or name

English

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publication date

1 August 2015

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volume

44

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issue

29

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page(s)

13125-13132

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Novel proteinaceous infectious particles cause scrapie

18 February 2020

cites work

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Prion diseases and neurodegeneration

21 January 2018

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Identification of a protein that purifies with the scrapie prion

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Identification of prion amyloid filaments in scrapie-infected brain

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A protease-resistant protein is a structural component of the scrapie prion

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Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

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Shattuck lecture--neurodegenerative diseases and prions

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The chemistry of copper binding to PrP: is there sufficient evidence to elucidate a role for copper in protein function?

21 January 2018

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NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

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Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

21 January 2018

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Molecular features of the copper binding sites in the octarepeat domain of the prion protein

21 January 2018

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Copper binding to the octarepeats of the prion protein. Affinity, specificity, folding, and cooperativity: insights from circular dichroism

21 January 2018

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Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases.

21 January 2018

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CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides

21 January 2018

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Preferential Cu2 coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein

21 January 2018

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Fragment length influences affinity for Cu2 and Ni2 binding to His96 or His111 of the prion protein and spectroscopic evidence for a multiple histidine binding only at low pH.

21 January 2018

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Thermodynamic and spectroscopic investigation on the role of Met residues in Cu(II) binding to the non-octarepeat site of the human prion protein

21 January 2018

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Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4.

21 January 2018

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A reassessment of copper(II) binding in the full-length prion protein

21 January 2018

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Both Met(109) and Met(112) are utilized for Cu(II) coordination by the amyloidogenic fragment of the human prion protein at physiological pH.

21 January 2018

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Copper coordination in the full-length, recombinant prion protein

21 January 2018

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The cellular prion protein binds copper in vivo

21 January 2018

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Location and properties of metal-binding sites on the human prion protein.

21 January 2018

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Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis).

21 January 2018

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Can copper binding to the prion protein generate a misfolded form of the protein?

21 January 2018

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Hyperquad simulation and speciation (HySS): a utility program for the investigation of equilibria involving soluble and partially soluble species

21 January 2018

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Torsion angle dynamics for NMR structure calculation with the new program Dyana

21 January 2018

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Interactions between the Conserved Hydrophobic Region of the Prion Protein and Dodecylphosphocholine Micelles

21 January 2018

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Secondary structure conversions of Alzheimer's Abeta(1-40) peptide induced by membrane-mimicking detergents

21 January 2018

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Solution structures of micelle-bound amyloid beta-(1-40) and beta-(1-42) peptides of Alzheimer's disease

21 January 2018

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A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

21 January 2018

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Structure and dynamics of micelle-bound human alpha-synuclein

21 January 2018

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Copper-induced structural propensities of the amyloidogenic region of human prion protein

21 January 2018

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Structural and Dynamic Characterization of Copper(II) Binding of the Human Prion Protein Outside the Octarepeat Region

21 January 2018

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The complex-formation behaviour of His residues in the fifth Cu2 binding site of human prion protein: a close look

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/C5DT01488C

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18 February 2020

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