Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit (Q40757122)

23 September 2017

title

Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit (English)

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23 September 2017

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simian virus 40

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7

Roger R Reddel

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23 September 2017

Christian D Toouli

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23 September 2017

Lily I Huschtscha

2

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23 September 2017

Axel A Neumann

3

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23 September 2017

Jane R Noble

4

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23 September 2017

Lorel M Colgin

5

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23 September 2017

Bharati Hukku

6

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23 September 2017

language of work or name

English

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publication date

1 January 2002

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23 September 2017

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23 September 2017

volume

21

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23 September 2017

issue

1

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23 September 2017

page(s)

128-139

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describes a project that uses

23 September 2017

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Genetic instability as a consequence of inappropriate entry into and progression through S-phase.

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Structure and function of telomeres

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

SV40-induced immortalization of human cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Telomere maintenance mechanisms and cellular immortalization.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Genetic and epigenetic changes in human epithelial cells immortalized by telomerase

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Inactivation of p16 in human mammary epithelial cells by CpG island methylation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Viral oncogenes accelerate conversion to immortality of cultured conditionally immortal human mammary epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Telomere loss: mitotic clock or genetic time bomb?

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

The serial cultivation of human diploid cell strains

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Immortalization of human CD8 T cell clones by ectopic expression of telomerase reverse transcriptase

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and response to SV40 transfection

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8 T lymphocyte immortalization

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

The telomerase reverse transcriptase: components and regulation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

13 Cell culture characterization: Monitoring for cell identification

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Telomere dynamics in a human cancer cell line.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Control of telomere length by the human telomeric protein TRF1

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Loss of p53 protein during radiation transformation of primary human mammary epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Human endothelial cell life extension by telomerase expression

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Malignant progression of SV40-immortalised human milk epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

7 January 2021

Loss of chromosome 3p arm differentiating tumorigenic from non-tumorigenic cells derived from the same SV40-transformed human mammary epithelial cells

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

7 January 2021

Human cell transformation by simian virus 40—A review

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

7 January 2021

Flow cytometric DNA analyses of frozen samples from children's solid tumors

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

7 January 2021

Isolation and growth of human mammary epithelial cells

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https://api.crossref.org/works/10.1038/SJ.ONC.1205014

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205014

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Dimensions Publication ID

23 September 2017

1036876540

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