Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1. (Q40753304)

23 September 2017

title

Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1. (English)

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23 September 2017

7

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23 September 2017

Christa Cerni

1

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23 September 2017

Barbara Skrzypek

2

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23 September 2017

Nikita Popov

3

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23 September 2017

Soleman Sasgary

4

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23 September 2017

Gerlinde Schmidt

5

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23 September 2017

Lars-Gunnar Larsson

6

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23 September 2017

Marie Henriksson

8

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23 September 2017

language of work or name

English

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publication date

1 January 2002

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23 September 2017

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23 September 2017

volume

21

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23 September 2017

issue

3

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23 September 2017

page(s)

447-459

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

23 September 2017

cites work

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Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

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Inhibition of cell growth and apoptosis by inducible expression of the transcriptional repressor Mad1.

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter.

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Immortalization of primary rat embryo cells by human papillomavirus type 11 DNA is enhanced upon cotransfer of ras.

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Telomeres, telomerase, and myc. An update

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Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells

21 January 2018

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The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

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Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

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Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation

21 January 2018

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Induction of telomerase activity in v-myc-transformed avian cells

21 January 2018

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Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation.

21 January 2018

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Inhibition of proliferation and apoptosis by the transcriptional repressor Mad1. Repression of Fas-induced caspase-8 activation

21 January 2018

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A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

21 January 2018

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High Efficiency DNA-Mediated Transformation of Primate Cells

21 January 2018

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The Myc/Max/Mad network and the transcriptional control of cell behavior

21 January 2018

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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

21 January 2018

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Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells

21 January 2018

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

21 January 2018

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

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Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites

21 January 2018

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Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif

21 January 2018

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Drosophila myc regulates cellular growth during development.

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1

21 January 2018

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

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Function and regulation of the transcription factors of the Myc/Max/Mad network

21 January 2018

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The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

21 January 2018

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The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

21 January 2018

1 reference

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Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Identification of Mad as a repressor of the human telomerase (hTERT) gene

21 January 2018

1 reference

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Gene-target recognition among members of the myc superfamily and implications for oncogenesis

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Suppression of src-induced transformed phenotype by expression of tropomyosin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Sequential expression of the MAD family of transcriptional repressors during differentiation and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Inhibition of cell proliferation by the Mad1 transcriptional repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Inducible expression of Mad accelerates growth arrest of serum deprived human glioblastoma cells.

21 January 2018

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A survey of telomerase activity in human cancer

21 January 2018

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Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro

21 January 2018

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21 January 2018

Myc activates telomerase

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Direct activation of TERT transcription by c-MYC.

21 January 2018

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Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

Function of the c-Myc oncoprotein in chromatin remodeling and transcription.

21 January 2018

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7 January 2021

myc family oncogenes in the development of normal and neoplastic cells.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

7 January 2021

Clinical implication of altered expression of Mad1 protein in human breast carcinoma

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

7 January 2021

Induction of p21WAF1 expression via Sp1-binding sites by tamoxifen in estrogen receptor-negative lung cancer cells

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https://api.crossref.org/works/10.1038/SJ.ONC.1205107

7 January 2021

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205107

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205107

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Dimensions Publication ID

23 September 2017

1010041524

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