Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. (Q40722521)

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10 November 2019

title

Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1 (English)

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10 November 2019

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11

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10 November 2019

Monika E Hegi

12

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10 November 2019

author name string

Michele Albertoni

1

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10 November 2019

Phillip H Shaw

2

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10 November 2019

Michimasa Nozaki

3

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10 November 2019

Sophie Godard

4

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10 November 2019

Mirna Tenan

5

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10 November 2019

Marie-France Hamou

6

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10 November 2019

Douglas W Fairlie

7

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10 November 2019

Samuel N Breit

8

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10 November 2019

Vishwas M Paralkar

9

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10 November 2019

Nicolas de Tribolet

10

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10 November 2019

language of work or name

English

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publication date

1 June 2002

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10 November 2019

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10 November 2019

volume

21

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10 November 2019

issue

27

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10 November 2019

page(s)

4212-4219

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Genetic instability leads to loss of both p53 alleles in a human glioblastoma

10 November 2019

cites work

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The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-beta superfamily member, acts as a quality control determinant for correctly folded MIC-1.

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MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

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Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1).

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

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Redox regulation of p53 during hypoxia

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Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis

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Epitope mapping of the transforming growth factor-beta superfamily protein, macrophage inhibitory cytokine-1 (MIC-1): identification of at least five distinct epitope specificities

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Transcriptional activation by tetracyclines in mammalian cells

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PLAB, a novel placental bone morphogenetic protein

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Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury

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Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

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Profile of gene expression regulated by induced p53: connection to the TGF-beta family

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Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta

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Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression

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Transforming growth factor beta 1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells.

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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

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Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

21 January 2018

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Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia

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Expression of growth differentiation factor-15/ macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in the perinatal, adult, and injured rat brain

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7 January 2021

Lineage-restricted expression of bone morphogenetic protein genes in human hematopoietic cell lines

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7 January 2021

MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation

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7 January 2021

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Growth/differentiation factor-15/macrophage inhibitory cytokine-1 is a novel trophic factor for midbrain dopaminergic neurons in vivo

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205610

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082608 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 November 2019

1038589095

0 references

1 reference