Programmed cell death--many questions still to be answered (Q40699839)

22 September 2017

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title

Programmed cell death--many questions still to be answered (English)

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22 September 2017

C Binder

1

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22 September 2017

W Hiddemann

series ordinal

2

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22 September 2017

publication date

1 August 1994

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22 September 2017

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22 September 2017

volume

69

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22 September 2017

issue

2

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22 September 2017

page(s)

45-55

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Apoptosis (the 1992 Frank Rose Memorial Lecture).

22 September 2017

cites work

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

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Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes

21 January 2018

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Effects of cycloheximide on B-chronic lymphocytic leukaemic and normal lymphocytes in vitro: induction of apoptosis

21 January 2018

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Tumour necrosis factor-induced cytotoxicity is accompanied by intracellular mitogenic signals in ME-180 human cervical carcinoma cells

21 January 2018

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Identification of mRNAs associated with programmed cell death in immature thymocytes

21 January 2018

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Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells

21 January 2018

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Effects of histone acetylation, ubiquitination and variants on nucleosome stability

21 January 2018

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Ubiquitin pathway involvement in human lymphocyte gamma-irradiation-induced apoptosis

21 January 2018

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Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability

21 January 2018

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Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2

21 January 2018

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

1 reference

12 December 2020

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

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12 December 2020

Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways

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12 December 2020

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

1 reference

12 December 2020

Effect of bcl-2 on Fas antigen-mediated cell death

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12 December 2020

The formation of plasma membrane blebs in hepatocytes exposed to agents that increase cytosolic Ca2 is mediated by the activation of a non-lysosomal proteolytic system

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12 December 2020

Cell death: the significance of apoptosis

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12 December 2020

Cyclic AMP potentiates glucocorticoid-induced endogenous endonuclease activation in thymocytes

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12 December 2020

Rapid apoptotic cell death of B‐cell hybridomas in absence of gene expression

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12 December 2020

Social controls on cell survival and cell death

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12 December 2020

Etoposide-induced cytotoxicity in two human T-cell leukemic lines: delayed loss of membrane permeability rather than DNA fragmentation as an indicator of programmed cell death

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12 December 2020

Rescue from programmed cell death in leukemic and normal myeloid cells

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12 December 2020

Glucocorticoid-induced cell death and poly[adenosine diphosphate(ADP)-ribosyl]ation: increased toxicity of dexamethasone on mouse S49.1 lymphoma cells with the poly(ADP-ribosyl)ation inhibitor benzamide

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12 December 2020

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

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12 December 2020

Apoptosis in toremifene-induced growth inhibition of human breast cancer cells in vivo and in vitro

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12 December 2020

bcl-2 inhibits death of central neural cells induced by multiple agents

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12 December 2020

MYC rearrangements in histologically progressed follicular lymphomas

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12 December 2020

Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells

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12 December 2020

Role of nicotinamide adenine dinucleotide and adenosine triphosphate in glucocorticoid-induced cytotoxicity in susceptible lymphoid cells

1 reference

12 December 2020

Induction of endonuclease-mediated apoptosis in tumor cells by C-nitroso-substituted ligands of poly(ADP-ribose) polymerase

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12 December 2020

Programmed cell death (apoptosis) is induced rapidly and with positive cooperativity by activation of cyclic adenosine monophosphate-kinase I in a myeloid leukemia cell line

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12 December 2020

DNA strand breaks, NAD metabolism, and programmed cell death

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12 December 2020

Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression

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12 December 2020

Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity.

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12 December 2020

Cell cycle arrest of proliferating neuronal cells by serum deprivation can result in either apoptosis or differentiation.

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12 December 2020

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

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12 December 2020

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen

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12 December 2020

Alterations in deoxynucleoside triphosphate metabolism in DNA damaged cells: identification and consequences of poly(ADP-ribose) polymerase dependent and independent processes

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12 December 2020

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

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12 December 2020

Properties of some nuclear nucleases of rat thymocytes and their changes in radiation-induced apoptosis

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12 December 2020

Wild-type p53-triggered apoptosis is inhibited by bcl-2 in a v-myc-induced T-cell lymphoma line.

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12 December 2020

Dicing with death: dissecting the components of the apoptosis machinery.

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12 December 2020

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

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12 December 2020

Biochemical events in naturally occurring forms of cell death

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12 December 2020

Programmed death of nonproliferating androgen-independent prostatic cancer cells

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12 December 2020

Internucleosomal DNA cleavage and neuronal cell survival/death

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12 December 2020

Protection from tumor necrosis factor-mediated cytolysis by overexpression of plasminogen activator inhibitor type-2.

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12 December 2020

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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12 December 2020

Induction of apoptosis in fibroblasts by c-myc protein

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12 December 2020

The death programme in cultured sympathetic neurones can be suppressed at the posttranslational level by nerve growth factor, cyclic AMP, and depolarization

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12 December 2020

Nicotinamide protects target cells from cell-mediated cytolysis

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12 December 2020

Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cells

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12 December 2020

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

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12 December 2020

The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins.

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12 December 2020

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

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12 December 2020

Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas

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12 December 2020

Inhibition of poly(ADP-ribose) polymerase as a possible reason for activation of Ca2 /Mg2 -dependent endonuclease in thymocytes of irradiated rats

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12 December 2020

N-acetylcysteine inhibits apoptosis and decreases viral particles in HIV-chronically infected U937 cells

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12 December 2020

Do all programmed cell deaths occur via apoptosis?

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12 December 2020

Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.

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12 December 2020

Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors

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12 December 2020

Enhanced Expression of p53 mRNA and Protein in the Regressing Rat Ventral Prostate Gland

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12 December 2020

A novel domain within the 55 kd TNF receptor signals cell death

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12 December 2020

Control of programmed cell death in normal and leukemic cells: new implications for therapy.

1 reference

12 December 2020

Metabolic effects and kill of human T-cell leukemia by 5-deazaacyclotetrahydrofolate, a specific inhibitor of glycineamide ribonucleotide transformylase

1 reference

12 December 2020

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores

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12 December 2020

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death)

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12 December 2020

Abrogation of adriamycin toxicity in vivo by cycloheximide

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12 December 2020

Fas involvement in Ca(2 )-independent T cell-mediated cytotoxicity

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12 December 2020

Regulation of two forms of the TNF receptors by phorbol ester and dibutyryl cyclic adenosine 3',5'-monophosphate in human histiocytic lymphoma cell line U-937.

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12 December 2020

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

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12 December 2020

An evolutionary perspective on apoptosis.

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12 December 2020

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

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12 December 2020

Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note

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12 December 2020

Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.

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12 December 2020

Growth factors as survival factors: regulation of apoptosis

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12 December 2020

Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells

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12 December 2020

Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine

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12 December 2020

Mitochondrial DNA is not fragmented during apoptosis

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12 December 2020

Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block

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12 December 2020

Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin

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12 December 2020

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

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12 December 2020

APO‐1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: Correlation with bcl‐2 oncogene expression

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12 December 2020

Molecular regulation of apoptosis: genetic controls on cell death.

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12 December 2020

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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12 December 2020

Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells

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12 December 2020

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

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12 December 2020

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

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12 December 2020

Bcl-2 initiates a new category of oncogenes: regulators of cell death

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12 December 2020

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

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12 December 2020

Glucose depletion enhances the anti-tumor effect of TNF.

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12 December 2020

Tyrosine kinase(s) regulate apoptosis and bcl-2 expression in a growth factor-dependent cell line.

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12 December 2020

Toward an understanding of the molecular mechanisms of physiological cell death.

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12 December 2020

Apoptosis in C3H/10T1/2 mouse embryonic cells: evidence for internucleosomal DNA modification in the absence of double-strand cleavage

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12 December 2020

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

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12 December 2020

Cell death in the oligodendrocyte lineage

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12 December 2020

Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis

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12 December 2020

Poly(ADP-ribose) synthase is the major endogenous nonhistone acceptor for poly(ADP-ribose) in alkylated rat hepatoma cells

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12 December 2020

Effects of c-myc expression on proliferation, quiescence, and the G0 to G1 transition in nontransformed cells.

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12 December 2020

Inhibition of apoptosis by zinc: a reappraisal.

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12 December 2020

Tumor necrosis factor alpha induces apoptosis in mammary adenocarcinoma cells by an increase in intranuclear free Ca2 concentration and DNA fragmentation

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12 December 2020

Activation of human peripheral blood mononuclear cells by nitric oxide-generating compounds

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12 December 2020

Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2( )-requiring mechanism(s).

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12 December 2020

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation

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12 December 2020

Pro-oxidants and mitochondrial Ca2 : their relationship to apoptosis and oncogenesis

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12 December 2020

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

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12 December 2020

Calyculin A, a potent inhibitor of phosphatases-1 and -2A, prevents apoptosis

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12 December 2020

Mechanism of tissue-specific induction of internucleosomal deoxyribonucleic acid cleavage activity and apoptosis by glucocorticoids

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12 December 2020

bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia

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12 December 2020

Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation

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12 December 2020

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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12 December 2020

Role of poly(ADP-ribose) formation in DNA repair

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12 December 2020

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

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12 December 2020

Activation of Programmed Cell Death by Recombinant Human Tumor Necrosis Factor Plus Topoisomerase II - Targeted Drugs in L929 Tumor Cells

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12 December 2020

Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin

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12 December 2020

Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation

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12 December 2020

Mechanism of epipodophyllotoxin-induced cell death in poly(adenosine diphosphate-ribose) synthesis-deficient V79 Chinese hamster cell lines.

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12 December 2020

Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle.

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12 December 2020

Identification of deoxyribonuclease II as an endonuclease involved in apoptosis

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12 December 2020

Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification

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12 December 2020

bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.

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12 December 2020

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

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12 December 2020

DNA damage increases the levels of MDM2 messenger RNA in wtp53 human cells

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12 December 2020

Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose

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12 December 2020

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

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12 December 2020

Synergistic induction of apoptosis with glucocorticoids and 3',5'-cyclic adenosine monophosphate reveals agonist activity by RU 486.

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12 December 2020

Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis

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12 December 2020

Fluctuations and ultrastructural localization of oncoproteins and cell cycle regulatory proteins during growth and apoptosis of synchronized AGF cells

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12 December 2020

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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12 December 2020

Cell death mechanisms and the immune system

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12 December 2020

VP-16-induced nucleotide pool changes and poly(ADP-ribose) synthesis: the role of VP-16 in interphase death

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12 December 2020

Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion

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12 December 2020

Apoptosis and DNA fragmentation precede TNF-induced cytolysis in U937 cells

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12 December 2020

Antiapoptotic effect of heterozygously expressed mutant RI (Ala336-->Asp) subunit of cAMP kinase I in a rat leukemia cell line

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12 December 2020

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

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12 December 2020

Tumor necrosis factor-mediated cytotoxicity involves ADP-ribosylation

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12 December 2020

Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

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12 December 2020

IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells

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12 December 2020

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

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12 December 2020

Apoptosis and Its Modulation in Human Promyelocytic HL-60 Cells Treated with DNA Topoisomerase I and II Inhibitors

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12 December 2020

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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12 December 2020

Nitric oxide-mediated apoptosis in murine peritoneal macrophages

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12 December 2020

Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes

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12 December 2020

Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes

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12 December 2020

Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death

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12 December 2020

Cytotoxic effects of cell cycle phase specific agents: result of cell cycle perturbation

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12 December 2020

Stable expression of the calbindin-D28K complementary DNA interferes with the apoptotic pathway in lymphocytes

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12 December 2020

Studies of the relationship between cell proliferation and cell death. II. Early gene expression during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes.

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12 December 2020

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis

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12 December 2020

Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens

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12 December 2020

The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents

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12 December 2020

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

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12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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12 December 2020

Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans

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12 December 2020

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

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12 December 2020

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

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12 December 2020

Evidence for adenosine diphosphate ribosylation of Ca2 , Mg2 -dependent endonuclease

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12 December 2020

Cyclic adenosine monophosphate promotes cell survival and retards apoptosis in a factor-dependent bone marrow-derived cell line

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12 December 2020

Protein kinases negatively affect nuclear factor-kappa B activation by tumor necrosis factor-alpha at two different stages in promyelocytic HL60 cells

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12 December 2020

Identifiers

DOI

10.1007/BF01698481

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22 September 2017

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