TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling. (Q40698636)

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14 March 2020

title

TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling (English)

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Mar Lorente

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Patricia Zúñiga García

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Cristina Sánchez

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Nelson Dusetti

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Endre Kiss-Toth

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Sheila E Francis

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Sonia Hernández-Tiedra

12

object named as

Sonia Hernández-Tiedra

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Juan L Iovanna

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3

Elena García-Taboada

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Israel López-Valero

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Arkaitz Carracedo

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14 March 2020

author name string

María Salazar

1

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14 March 2020

Eduardo Pérez Gómez

4

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David Dávila

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Juana M Flores

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Antonio Rodríguez

8

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Zoltan Hegedus

9

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David Mosén-Ansorena

10

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Ana M Aransay

11

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Miguel Quintanilla

14

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Manuel Guzmán

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publication date

18 April 2015

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Molecular & cellular oncology

14 March 2020

published in

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14 March 2020

volume

2

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14 March 2020

issue

3

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14 March 2020

page(s)

e980134

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Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation.

14 March 2020

cites work

1 reference

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High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer.

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Pseudokinases-remnants of evolution or key allosteric regulators?

25 September 2017

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Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

25 September 2017

1 reference

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TRB3 interacts with CtIP and is overexpressed in certain cancers

25 September 2017

1 reference

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Human tribbles, a protein family controlling mitogen-activated protein kinase cascades

25 September 2017

1 reference

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TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

25 September 2017

1 reference

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The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action.

25 September 2017

1 reference

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Towards the use of cannabinoids as antitumour agents

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27308456