A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells. (Q40616617)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14615489 AND SRC:MED&resulttype=core&format=json

21 December 2019

title

A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells (English)

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21 December 2019

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5

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21 December 2019

author name string

Deepali Sachdev

1

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21 December 2019

Julie S Hartell

2

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21 December 2019

Adrian V Lee

3

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21 December 2019

Xihong Zhang

4

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21 December 2019

language of work or name

English

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publication date

13 November 2003

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Journal of Biological Chemistry

21 December 2019

published in

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21 December 2019

volume

279

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21 December 2019

issue

6

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21 December 2019

page(s)

5017-5024

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

21 December 2019

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

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Role of the insulin-like growth factor family in cancer development and progression

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Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice

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Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth

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Enhanced Invasion and Liver Colonization by Lung Carcinoma Cells Overexpressing the Type 1 Insulin-Like Growth Factor Receptor

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Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin

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Interaction of the .alpha..beta. dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation

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Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant

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MDA435/LCC6 and MDA435/LCC6MDR1: ascites models of human breast cancer.

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Systematic variation in gene expression patterns in human cancer cell lines

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Further evidence to support the melanocytic origin of MDA-MB-435

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Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines

21 January 2018

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Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

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Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells.

21 January 2018

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Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase.

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Dissemination and growth of cancer cells in metastatic sites

21 January 2018

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Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis

21 January 2018

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Analysis of gene expression involved in brain metastasis from breast cancer using cDNA microarray

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305403200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14615489 AND SRC:MED&resulttype=core&format=json

21 December 2019

1 reference