V(D)J recombination and double-strand break repair (Q40519651)

21 September 2017

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title

V(D)J recombination and double-strand break repair (English)

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21 September 2017

D T Weaver

1

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21 September 2017

publication date

1 January 1995

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21 September 2017

published in

Advances in Immunology

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21 September 2017

volume

58

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21 September 2017

page(s)

29-85

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Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining

21 September 2017

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Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells

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7 January 2021

Selection is not required to produce invariant T-cell receptor gamma-gene junctional sequences.

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7 January 2021

The mechanism of chromosome 14 inversion in a human T cell lymphoma.

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7 January 2021

The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis

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7 January 2021

Suppression of human colorectal carcinoma cell growth by wild-type p53

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7 January 2021

Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8

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7 January 2021

Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents

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7 January 2021

Nonhomologous DNA end joining of synthetic hairpin substrates in Xenopus laevis egg extracts

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7 January 2021

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

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7 January 2021

The mouse mutation severe combined immune deficiency (scid) is on chromosome 16.

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7 January 2021

A severe combined immunodeficiency mutation in the mouse

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7 January 2021

The SCID mouse mutant: definition, characterization, and potential uses

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7 January 2021

V(D)J recombination coding junction formation without DNA homology: processing of coding termini

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7 January 2021

Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues.

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7 January 2021

A DNA-activated protein kinase from HeLa cell nuclei

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7 January 2021

Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency

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https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

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https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

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https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

T-cell receptor delta gene rearrangements in early thymocytes

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https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Requirement for the replication protein SSB in human DMA excision repair

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7 January 2021

Juxtaposition of the T-cell receptor alpha-chain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia

1 reference

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7 January 2021

Restricted heterogeneity of T lymphocytes in combined immunodeficiency with hypereosinophilia (Omenn's syndrome).

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

p53 functions as a cell cycle control protein in osteosarcomas

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Defective repair of radiation-induced chromosomal damage in scid/scid mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Multiple components are involved in the efficient joining of double stranded DNA breaks in human cell extracts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The nucleotide sequence of a mouse cDNA encoding the 80 kDa subunit of the Ku (p70/p80) autoantigen

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Wild-type p53 activates transcription in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The scid mutation in mice causes a general defect in DNA repair

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Unequal signal and coding joint formation in human V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Molecular analysis of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

V(D)J recombination gets a break

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Coding end sequence can markedly affect the initiation of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Cell cycle-dependent repair of double-strand DNA breaks in a gamma-ray-sensitive Chinese hamster cell

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Increased sensitivity to killing by restriction enzymes in the XR-1 DNA double-strand break repair-deficient mutant

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Genetic linkage of Werner's syndrome to five markers on chromosome 8

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Subchromosomal localization of a gene (XRCC5) involved in double strand break repair to the region 2q34-36.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A new protein motif found in DNA joining and DNA binding proteins.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Gene recombination in X-ray-sensitive hamster cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Analysis of the defect in DNA end joining in the murine scid mutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Checkpoints: controls that ensure the order of cell cycle events

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Wild-type V(D)J recombination in scid pre-B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Breakage of the T cell receptor alpha chain locus in non malignant clones from patients with ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

V(D)J recombination: a functional definition of the joining signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Growth of large chromosomally abnormal T cell clones in ataxia telangiectasia patients is associated with translocation at 14q11. A model for other T cell neoplasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

V(D)J recombination: evidence that a replicative mechanism is not required

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Abnormalities in DNA rearrangements of immunoglobulin gene loci in precursor B cells derived from X-linked agammaglobulinemia patient and a severe combined immunodeficiency patient.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Localization of a DNA repair gene (XRCC5) involved in double-strand-break rejoining to human chromosome 2

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A hamster-human subchromosomal hybrid cell panel for chromosome 2

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Repair of deletions and double-strand gaps by homologous recombination in a mammalian in vitro system

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Chemical Nature of Chain Breaks Produced in DNA by X-Irradiation in Vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Identification of p53 as a sequence-specific DNA-binding protein

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

T cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertion

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Functional complementation in mouse-human radiation hybrids assigns the putative murine scid gene to the pericentric region of human chromosome 8.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Murine scid cells complement ataxia-telangiectasia cells and show a normal post-irradiation response of DNA synthesis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

p53: oncogene or anti-oncogene?

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The mechanism of antigen receptor gene assembly

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Site‐specific recombination in the immune system 1

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Cloning and expression of a novel human DNA binding protein, PO-GA

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Cloning, expression, and chromosomal localization of the 140-kilodalton subunit of replication factor C from mice and humans

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

P nucleotides in V(D)J recombination: a fine-structure analysis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Analysis of a T-cell tumor-specific breakpoint cluster at human chromosome 14q32.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The mouse severe combined immune deficiency (scid) mutation is closely linked to the B-cell-specific developmental genes VpreB and lambda 5.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Homologous recombination in a Chinese hamster X-ray-sensitive mutant.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Analysis of the mechanism of interaction of simian Ku protein with DNA

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Repair replication in mammalian cells after x-irradiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Radiosensitivity in ataxia-telangiectasia: a new explanation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Resolution and conservation of mismatches in DNA end joining.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Mechanisms of overlap formation in nonhomologous DNA end joining

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Joining of nonhomologous DNA double strand breaks in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Ciba Medal Lecture. Chromosomal abnormalities in cancer cells: identification of molecules important for tumour development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Evidence for a general relationship between the induced level of DNA double-strand breakage and cell-killing after X-irradiation of mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Conservation of sequence in recombination signal sequence spacers

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A DNA end-binding factor involved in double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Mechanisms of nonhomologous recombination in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Molecular analysis of a t(7;14)(q35;q32) chromosome translocation in a T cell leukemia of a patient with ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

V(D)J recombination: molecular biology and regulation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The V(D)J recombination activating gene, RAG-1.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Homozygosity mapping and Werner's syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: unusual P-nucleotide additions in VJ-coding joints

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Severe combined immunodeficiency (SCID) in man: B cell-negative (B-) SCID patients exhibit an irregular recombination pattern at the JH locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

scid cells efficiently integrate hairpin and linear DNA substrates

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Severe combined immunodeficiency: a retrospective single-center study of clinical presentation and outcome in 117 patients

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

The scid mutation in mice causes defects in the repair system for both double-strand DNA breaks and DNA cross-links

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

A novel pathway of DNA end-to-end joining

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

1 reference

7 January 2021

Growth retardation and immunodeficiency in a patient with mutations in the DNA ligase I gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Cell cycle responses of two X-ray sensitive mutants defective in DNA repair

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

Novel T-lymphocyte population in combined immunodeficiency with features of graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

On the mechanisms of ku protein binding to DNA

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(08)60619-7

7 January 2021

10.1016/S0065-2776(08)60619-7

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