The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions (Q40519553)

21 September 2017

The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions (English)

1 reference

21 September 2017

Pseudomonas aeruginosa

1 reference

based on heuristic

inferred from title

antimicrobial peptide

1 reference

6

Søren Molin

0 references

Rasmus L Marvig

object named as

Rasmus L Marvig

2

0 references

Anders Folkesson

object named as

Anders Folkesson

8

0 references

Lars Jelsbak

object named as

Lars Jelsbak

7

0 references

author name string

Nicholas Jochumsen

1

1 reference

21 September 2017

Søren Damkiær

3

1 reference

21 September 2017

Rune Lyngklip Jensen

4

1 reference

21 September 2017

Wilhelm Paulander

5

1 reference

21 September 2017

language of work or name

English

0 references

publication date

3 October 2016

1 reference

21 September 2017

Nature Communications

1 reference

21 September 2017

7

1 reference

21 September 2017

13002

1 reference

Creative Commons Attribution 4.0 International

21 September 2017

start time

3 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Evolved resistance to colistin and its loss due to genetic reversion in Pseudomonas aeruginosa

1 reference

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Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes

22 September 2017

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Experimental evolution reveals hidden diversity in evolutionary pathways.

22 September 2017

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Colistin, mechanisms and prevalence of resistance

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Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

22 September 2017

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22 September 2017

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Genome analysis of a transmissible lineage of pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators

22 September 2017

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Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts

22 September 2017

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Polymyxin resistance of Pseudomonas aeruginosa phoQ mutants is dependent on additional two-component regulatory systems

22 September 2017

1 reference

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22 September 2017

1 reference

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The two-component system CprRS senses cationic peptides and triggers adaptive resistance in Pseudomonas aeruginosa independently of ParRS

22 September 2017

1 reference

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Genomic analysis of a key innovation in an experimental Escherichia coli population

22 September 2017

1 reference

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Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

22 September 2017

1 reference

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PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients

22 September 2017

1 reference

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PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

22 September 2017

1 reference

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A Mig-14-like protein (PA5003) affects antimicrobial peptide recognition in Pseudomonas aeruginosa

22 September 2017

1 reference

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Diminishing returns epistasis among beneficial mutations decelerates adaptation

22 September 2017

1 reference

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Evolutionary dynamics of bacteria in a human host environment

22 September 2017

1 reference

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

22 September 2017

1 reference

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Adaptive resistance to the "last hope" antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS

22 September 2017

1 reference

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Microindel detection in short-read sequence data

22 September 2017

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Stepwise acquisition of pyrimethamine resistance in the malaria parasite

22 September 2017

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22 September 2017

1 reference

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Accelerated evolution of resistance in multidrug environments

22 September 2017

1 reference

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Impact of individual mutations on increased fitness in adaptively evolved strains of Escherichia coli

22 September 2017

1 reference

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Opr86 is essential for viability and is a potential candidate for a protective antigen against biofilm formation by Pseudomonas aeruginosa

22 September 2017

1 reference

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Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

22 September 2017

1 reference

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Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria

22 September 2017

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Multi-targeting by monotherapeutic antibacterials.

22 September 2017

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Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections

22 September 2017

1 reference

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Darwinian evolution can follow only very few mutational paths to fitter proteins

22 September 2017

1 reference

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An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants

22 September 2017

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The contribution of epistasis to the architecture of fitness in an RNA virus

22 September 2017

1 reference

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PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A

22 September 2017

1 reference

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Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa

22 September 2017

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Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa

22 September 2017

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Discovery and development of new antibiotics: the problem of antibiotic resistance

22 September 2017

1 reference

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Cloning and phenotypic characterization of fleS and fleR, new response regulators of Pseudomonas aeruginosa which regulate motility and adhesion to mucin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

22 September 2017

1 reference

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Fatty acid alterations and polymyxin B binding by lipopolysaccharides from Pseudomonas aeruginosa adapted to polymyxin B resistance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Lipid and lipopolysaccharide composition of Escherichia coli surface-altered mutants selected for resistance to levallorphan, tetracaine, and polymyxin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Polymyxin and Related Peptide Antibiotics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Pseudomonas aeruginosa high-level resistance to polymyxins and other antimicrobial peptides requires cprA, a gene that is disrupted in the PAO1 strain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Differential Role of Two-Component Regulatory Systems (phoPQ and pmrAB) in Polymyxin B Susceptibility of Pseudomonas aeruginosa

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Characterization of the lipopolysaccharide from the polymyxin-resistantpmrAmutants ofSalmonella typhimurium

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

An enzyme from bacteria able to destroy penicillin. 1940.

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

Negative epistasis between beneficial mutations in an evolving bacterial population

20 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494192

An Enzyme from Bacteria able to Destroy Penicillin

20 August 2018

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Crossref

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Nebulised colomycin for early pseudomonas colonisation in cystic fibrosis

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27694971

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS13002

1 reference

21 September 2017

0 references

1 reference

21 September 2017

PubMed publication ID

27694971

1 reference