A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria. (Q40498233)

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4 January 2020

title

A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria (English)

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4 January 2020

6

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4 January 2020

5

Yusuf A Hannun

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4 January 2020

author name string

Helene Birbes

1

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4 January 2020

Chiara Luberto

2

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4 January 2020

Yi-Te Hsu

3

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4 January 2020

Samer El Bawab

4

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4 January 2020

language of work or name

English

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publication date

1 March 2005

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4 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15516208 AND SRC:MED&resulttype=core&format=json

4 January 2020

volume

386

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issue

Pt 3

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4 January 2020

page(s)

445-451

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

4 January 2020

cites work

1 reference

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Mitochondria and ceramide: intertwined roles in regulation of apoptosis

22 September 2017

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

22 September 2017

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TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

22 September 2017

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22 September 2017

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Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury

22 September 2017

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22 September 2017

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Akt regulates cell survival and apoptosis at a postmitochondrial level

22 September 2017

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

22 September 2017

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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

22 September 2017

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Molecular cloning and characterization of a human mitochondrial ceramidase

22 September 2017

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Ceramide in the eukaryotic stress response

22 September 2017

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

22 September 2017

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IAP family proteins--suppressors of apoptosis

22 September 2017

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Regulated targeting of BAX to mitochondria.

22 September 2017

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22 September 2017

Caspases: enemies within

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

22 September 2017

1 reference

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p53-dependent ceramide response to genotoxic stress

22 September 2017

1 reference

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Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

22 September 2017

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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

22 September 2017

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

22 September 2017

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Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction

22 September 2017

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Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells.

17 June 2018

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3 July 2018

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Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase

20 August 2018

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Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

20 August 2018

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Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

20 August 2018

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Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

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12 December 2020

Involvement of p27(kip1) in ceramide-mediated apoptosis in HL-60 cells

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12 December 2020

Early transitory rise in intracellular pH leads to Bax conformation change during ceramide-induced apoptosis

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12 December 2020

Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation

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12 December 2020

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

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12 December 2020

Direct Inhibition of Mitochondrial Respiratory Chain Complex III by Cell-permeable Ceramide

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12 December 2020

Role of an acidic compartment in tumor‐necrosis‐factor‐α−induced production of ceramide, activation of caspase‐3 and apoptosis

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12 December 2020

Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

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12 December 2020

Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A

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12 December 2020

Identifiers

DOI

10.1042/BJ20041627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15516208 AND SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

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4 January 2020

PubMed publication ID

15516208

1 reference