Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation (Q40496539)

21 September 2017

title

Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation (English)

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21 September 2017

2

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21 September 2017

Yulan Qing

1

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21 September 2017

Diane Watling

series ordinal

3

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21 September 2017

George R Stark

series ordinal

4

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21 September 2017

language of work or name

English

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publication date

1 November 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

280

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21 September 2017

issue

3

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21 September 2017

page(s)

1849-1853

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How cells respond to interferons

21 September 2017

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Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

21 January 2018

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21 January 2018

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SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

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The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

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Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

21 January 2018

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The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.

21 January 2018

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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

21 January 2018

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Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mutation of the SHP-2 Binding Site in Growth Hormone (GH) Receptor Prolongs GH-Promoted Tyrosyl Phosphorylation of GH Receptor, JAK2, and STAT5B

21 January 2018

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

21 January 2018

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Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

21 January 2018

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Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130

21 January 2018

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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

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SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

21 January 2018

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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

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The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression

21 January 2018

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IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

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SOCS3 regulates the plasticity of gp130 signaling

21 January 2018

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SOCS3 negatively regulates IL-6 signaling in vivo

21 January 2018

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Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation

21 January 2018

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Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression

21 January 2018

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Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses.

21 January 2018

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Alternative activation of STAT1 and STAT3 in response to interferon-gamma

21 January 2018

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The Stat1 binding motif of the interferon-gamma receptor is sufficient to mediate Stat5 activation and its repression by SOCS3.

21 January 2018

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

21 January 2018

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Construction and analysis of an EMBL-3 phage library containing partially digested human chromosome 21-specific DNA inserts (15-20 kb).

21 January 2018

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Human chromosomes 6 and 21 are required for sensitivity to human interferon gamma

21 January 2018

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Identification of a functionally important sequence in the C terminus of the interferon-gamma receptor.

21 January 2018

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JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling

21 January 2018

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A family of cytokine-inducible inhibitors of signalling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M409863200

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21 September 2017

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